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ChemicalBook >> CAS DataBase List >>N-[6-(2,6-Dichlorophenyl)-2-[[4-(diethylamino)butyl]amino]pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)urea

N-[6-(2,6-Dichlorophenyl)-2-[[4-(diethylamino)butyl]amino]pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)urea

CAS No.
192705-80-9
Chemical Name:
N-[6-(2,6-Dichlorophenyl)-2-[[4-(diethylamino)butyl]amino]pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)urea
Synonyms
PD 161570;PF-1480232;PD-161570;PF-1480232;1-(tert-Butyl)-3-(6-(2,6-dichlorophenyl)-2-((4-(diethylamino)butyl)amino)pyrido[2,3-d]pyrimidi;1-Tert-butyl-3-[6-(2,6-dichloro-phenyl)-2-(4-diethylaMino-butylaMino)pyrido[2,3-d]pyriMidin-7-yl]urea;N-[6-(2,6-Dichlorophenyl)-2-[[4-(diethylamino)butyl]amino]pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)urea;Urea, N-[6-(2,6-dichlorophenyl)-2-[[4-(diethylamino)butyl]amino]pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)-;Inhibitor,Fibroblast growth factor receptor,HER1,kinases,autophosphorylation,PDGFR,PD161570,FGFR,Src,inhibit,TGF-β Receptor,ATP-competitive,Epidermal growth factor receptor,tyrosine,Platelet-derived growth factor receptor,disease,EGFR,anti-cancer,angiogenesis,ErbB-1,FGFR1,Transforming growth factor beta receptors,cardiovascular,anti-proliferation,PD-161570
CBNumber:
CB62518839
Molecular Formula:
C26H35Cl2N7O
Molecular Weight:
532.51
MDL Number:
MFCD16618403
MOL File:
192705-80-9.mol
MSDS File:
SDS
Last updated:2023-09-04 16:42:00

N-[6-(2,6-Dichlorophenyl)-2-[[4-(diethylamino)butyl]amino]pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)urea Properties

Melting point 215-230?C
Density 1.249±0.06 g/cm3(Predicted)
storage temp. Store at RT
solubility DMSO: >10mg/mL
form powder
pka 9.82±0.43(Predicted)
color white to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS06
Signal word  Danger
Hazard statements  H301-H315-H319-H335
Precautionary statements  P301+P310+P330-P302+P352-P305+P351+P338
Hazard Codes  T
Risk Statements  25-36/37/38
Safety Statements  26-45
RIDADR  UN 2811 6.1 / PGIII
WGK Germany  3
NFPA 704
0
2 0

N-[6-(2,6-Dichlorophenyl)-2-[[4-(diethylamino)butyl]amino]pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)urea price More Price(17)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PZ0109 PD-161570 ≥98% (HPLC) 192705-80-9 5mg $150 2024-03-01 Buy
Sigma-Aldrich PZ0109 PD-161570 ≥98% (HPLC) 192705-80-9 25mg $477 2024-03-01 Buy
Cayman Chemical 24681 PD 161570 ≥98% 192705-80-9 1mg $32 2024-03-01 Buy
Cayman Chemical 24681 PD 161570 ≥98% 192705-80-9 5mg $116 2024-03-01 Buy
Cayman Chemical 24681 PD 161570 ≥98% 192705-80-9 10mg $214 2024-03-01 Buy
Product number Packaging Price Buy
PZ0109 5mg $150 Buy
PZ0109 25mg $477 Buy
24681 1mg $32 Buy
24681 5mg $116 Buy
24681 10mg $214 Buy

N-[6-(2,6-Dichlorophenyl)-2-[[4-(diethylamino)butyl]amino]pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)urea Chemical Properties,Uses,Production

Chemical Properties

Off-White Solid

Uses

A novel FGF-1 receptor tyrosine kinase inhibitor which has been shown to effectively suppress constitutive phosphorylation of the FGF-1 receptor in human ovarian carcinoma cells.

Uses

PD-161570 is a novel FGF-1 receptor tyrosine kinase inhibitor, which has been shown to effectively suppress constitutive phosphorylation of the FGF-1 receptor in human ovarian carcinoma cells (1,2,3).

storage

Store at -20°C

N-[6-(2,6-Dichlorophenyl)-2-[[4-(diethylamino)butyl]amino]pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)urea Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 62)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32951 60
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32112 58
Nantong HI-FUTURE Biology Co., Ltd. 		+undefined18051384581 sales@chemhifuture.com China 3135 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 57505 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15839 69
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32321 50
TOKYO CHEMICAL INDUSTRY CO., LTD. 03-36680489 Sales-JP@TCIchemicals.com Japan 28387 80
Shanghai Aladdin Bio-Chem Technology Co.,LTD 400-400-6206333 18521732826 market@aladdin-e.com China 25003 65
ShangHai KenEn Chemical Technology Co., Ltd. 13120367189 mychess007@163.com China 1994 55

N-[6-(2,6-Dichlorophenyl)-2-[[4-(diethylamino)butyl]amino]pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)urea Spectrum

192705-80-9(N-[6-(2,6-Dichlorophenyl)-2-[[4-(diethylamino)butyl]amino]pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)urea)Related Search:

N-[6-(2,6-Dichlorophenyl)-2-[[4-(diethylamino)butyl]amino]pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)urea PD 161570 1-Tert-butyl-3-[6-(2,6-dichloro-phenyl)-2-(4-diethylaMino-butylaMino)pyrido[2,3-d]pyriMidin-7-yl]urea PF-1480232 PD-161570;PF-1480232 1-(tert-Butyl)-3-(6-(2,6-dichlorophenyl)-2-((4-(diethylamino)butyl)amino)pyrido[2,3-d]pyrimidi Inhibitor,Fibroblast growth factor receptor,HER1,kinases,autophosphorylation,PDGFR,PD161570,FGFR,Src,inhibit,TGF-β Receptor,ATP-competitive,Epidermal growth factor receptor,tyrosine,Platelet-derived growth factor receptor,disease,EGFR,anti-cancer,angiogenesis,ErbB-1,FGFR1,Transforming growth factor beta receptors,cardiovascular,anti-proliferation,PD-161570 Urea, N-[6-(2,6-dichlorophenyl)-2-[[4-(diethylamino)butyl]amino]pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)- 192705-80-9 C26H35Cl2N7O Aromatics Bases & Related Reagents Heterocycles Intermediates & Fine Chemicals Nucleotides Pfizer compounds Pharmaceuticals Tyrosine Kinase Inhibitors