7-hydroxy-2-methyl-4H-chromen-4-one
- CAS No.
- 6320-42-9
- Chemical Name:
- 7-hydroxy-2-methyl-4H-chromen-4-one
- Synonyms
- NSC 31894;Hymecromone EP Impurity B;7-Hydroxy-2-methylchromone;7-hydroxy-2-methylchromen-4-one;7-Hydroxy-2-methyl-4H-1-benzopyran-;7-hydroxy-2-methyl-1-benzopyran-4-one;7-Hydroxy-2-Methyl-4H-1-benzopyran-4-one;4H-1-Benzopyran-4-one, 7-hydroxy-2-Methyl-;Hymecromone Impurity 2 (Hymecromone EP Impurity B)
- CBNumber:
- CB62490146
- Molecular Formula:
- C10H8O3
- Molecular Weight:
- 176.17
- MDL Number:
- MFCD00208225
- MOL File:
- 6320-42-9.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319 |
| Precautionary statements | P261-P305+P351+P338 |
7-hydroxy-2-methyl-4H-chromen-4-one price More Price(16)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | Y0000013 | Hymecromone impurity B European Pharmacopoeia (EP) Reference Standard | 6320-42-9 | y0000013 | $161 | 2024-03-01 | Buy |
| TRC | H947035 | 7-Hydroxy-2-methyl-4H-chromen-4-one | 6320-42-9 | 100mg | $105 | 2021-12-16 | Buy |
| AK Scientific | 2754BB | 7-Hydroxy-2-methyl-4H-chromen-4-one | 6320-42-9 | 1g | $763 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0165657 | 7-HYDROXY-2-METHYL-4H-CHROMEN-4-ONE 95.00% | 6320-42-9 | 1G | $1351.35 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0165657 | 7-HYDROXY-2-METHYL-4H-CHROMEN-4-ONE 95.00% | 6320-42-9 | 5G | $2691.15 | 2021-12-16 | Buy |
7-hydroxy-2-methyl-4H-chromen-4-one Chemical Properties,Uses,Production
Uses
7-Hydroxy-2-methyl-4H-chromen-4-one is used in the synthesis of 2,2-Dimethyl-2H-pyranoflavonol and pyranochromone derivatives.
Synthesis
Step(i): 7-Acetoxy-3-acetyl-2-methylchromone
β-Resacetophenone (4.A.6) (10 g，0.066 mole) is heated with fusedsodium acetate (20 g) in acetic anhydride (30 ml) for 5 hr at 170-180°(oil bath) under anhydrous conditions. The reaction mixture is pouredover crushed ice, stirred well and left overnight.The separated product isfiltered and washed with water. It is crystallised from alcohol as light yellowneedles.Yield 10 g (58.5%).M.p.127° (lit. m.p.126-27°).
step (ii) : The above 7-acetoxy-3-acetyl-2-methylchromone (1 g,0.0038 mole) isrefluxed (2 hr) with aqueous sodium carbonate solution (10%,50 ml).Theclear solution is then acidified with hydrochloric acid (1:1).The separatedproduct is filtered and washed with water. It is crystallised from alcohol asthick prismatic crystals. Yield 0.5 g (73.5%).M.p. 249-50°.(lit. m.p.254-55°).
7-hydroxy-2-methyl-4H-chromen-4-one Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32951 | 60 |
| Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 | shawn@hirisunpharm.com | CHINA | 9911 | 58 |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19987 | 58 |
| sgtlifesciences pvt ltd | +8617013299288 | dj@sgtlifesciences.com | China | 12373 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| Shanghai Sinch Parmaceuticals Tech. Co. Ltd. | +86-21-54098501 | sales@sinch.com.cn | China | 11598 | 64 |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9976 | 60 |
| Hangzhou Sage Chemical Co., Ltd. | +86057186818502 13588463833 | info@sagechem.com | China | 10266 | 58 |
| Nanjing Credit Trading Co.,Ltd | 025-52164950 | Googlexu_0114@sina.com | China | 644 | 58 |