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ChemicalBook >> CAS DataBase List >>5-Chloro-N-[[[4-[6-fluoro-1,4-dihydro-7-(methylamino)-2,4-dioxo-3(2H)-quinazolinyl]phenyl]amino]carbonyl]-2-thiophenesulfonamide

5-Chloro-N-[[[4-[6-fluoro-1,4-dihydro-7-(methylamino)-2,4-dioxo-3(2H)-quinazolinyl]phenyl]amino]carbonyl]-2-thiophenesulfonamide

CAS No.
936500-94-6
Chemical Name:
5-Chloro-N-[[[4-[6-fluoro-1,4-dihydro-7-(methylamino)-2,4-dioxo-3(2H)-quinazolinyl]phenyl]amino]carbonyl]-2-thiophenesulfonamide
Synonyms
elinogrel;PRT 060128;P2Y Receptor,inhibit,PRT 060128,Elinogrel,Inhibitor,PRT-060128;5-Chloro-N-[[[4-[6-fluoro-1,4-dihydro-7-(MethylaMino)-2,4-dioxo-3(2H)-quinazolinyl]phenyl]aMino]carb;5-Chloro-N-((4-(6-fluoro-7-(methylamino)-2,4-dioxo-1,4-dihydroquinazolin-3(2H)-yl)phenyl)carbamoyl)thiophene-2-sulfonamide;5-Chloro-N-[[[4-[6-fluoro-1,4-dihydro-7-(methylamino)-2,4-dioxo-3(2H)-quinazolinyl]phenyl]amino]carbonyl]-2-thiophenesulfonamide;2-Thiophenesulfonamide, 5-chloro-N-[[[4-[6-fluoro-1,4-dihydro-7-(methylamino)-2,4-dioxo-3(2H)-quinazolinyl]phenyl]amino]carbonyl]-
CBNumber:
CB62484752
Molecular Formula:
C20H15ClFN5O5S2
Molecular Weight:
523.95
MDL Number:
MFCD16619373
MOL File:
936500-94-6.mol
Last updated:2024-07-02 08:55:13

5-Chloro-N-[[[4-[6-fluoro-1,4-dihydro-7-(methylamino)-2,4-dioxo-3(2H)-quinazolinyl]phenyl]amino]carbonyl]-2-thiophenesulfonamide Properties

Density 1.651
storage temp. Store at -20°C
solubility DMSO: 100 mM
form A solid
pka 4.42±0.10(Predicted)
color White to off-white
FDA UNII 915Y8E749J

5-Chloro-N-[[[4-[6-fluoro-1,4-dihydro-7-(methylamino)-2,4-dioxo-3(2H)-quinazolinyl]phenyl]amino]carbonyl]-2-thiophenesulfonamide price More Price(10)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 25976 Elinogrel ≥98% 936500-94-6 1mg $57 2024-03-01 Buy
Cayman Chemical 25976 Elinogrel ≥98% 936500-94-6 5mg $179 2024-03-01 Buy
Tocris 5316 Elinogrel ≥97%(HPLC) 936500-94-6 10 $235 2021-12-16 Buy
Tocris 5316 Elinogrel ≥97%(HPLC) 936500-94-6 50 $971 2021-12-16 Buy
TRC E508028 Elinogrel 936500-94-6 10mg $175 2021-12-16 Buy
Product number Packaging Price Buy
25976 1mg $57 Buy
25976 5mg $179 Buy
5316 10 $235 Buy
5316 50 $971 Buy
E508028 10mg $175 Buy

5-Chloro-N-[[[4-[6-fluoro-1,4-dihydro-7-(methylamino)-2,4-dioxo-3(2H)-quinazolinyl]phenyl]amino]carbonyl]-2-thiophenesulfonamide Chemical Properties,Uses,Production

Description

Elinogrel is a reversible antagonist of the platelet purinergic P2Y12 receptor (Ki = 23 nM) that inhibits platelet aggregation in a human platelet-rich plasma (hPRP) assay (IC50 = 2.81 nM). It inhibits thrombosis in a mouse model of vascular injury induced by iron (III) chloride (FeCl3) when administered at a dose of 60 mg/kg.

Uses

Elinogrel is a direct acting reversible P2Y12 inhibitor, which shows an antiplatelet effect and platelet reactivity associated with cytochrome P 450 2C19 and 3A5 gene polymorphisms.

storage

Store at -20°C

5-Chloro-N-[[[4-[6-fluoro-1,4-dihydro-7-(methylamino)-2,4-dioxo-3(2H)-quinazolinyl]phenyl]amino]carbonyl]-2-thiophenesulfonamide Preparation Products And Raw materials

Raw materials

Preparation Products

5-Chloro-N-[[[4-[6-fluoro-1,4-dihydro-7-(methylamino)-2,4-dioxo-3(2H)-quinazolinyl]phenyl]amino]carbonyl]-2-thiophenesulfonamide Suppliers

Global( 30)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32957 60
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49374 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32161 58
Career Henan Chemica Co 		+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30239 58
LEAPCHEM CO., LTD. 		+86-852-30606658 market18@leapchem.com China 43340 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 57505 58
Suzhou yacoo science co.,Ltd 0512-87182056 18013166090 lingling.qi@yacoo.com.cn China 7295 60
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9806 58
Shanghai Chaolan Chemical Technology Center 021-QQ：65489617 15618227136 Sales@ATKchemical.com China 7296 58
Hangzhou Synstar pharmaceutical Technology CO.,Ltd 0571-85361029 synstar518@163.com China 1990 58

5-Chloro-N-[[[4-[6-fluoro-1,4-dihydro-7-(methylamino)-2,4-dioxo-3(2H)-quinazolinyl]phenyl]amino]carbonyl]-2-thiophenesulfonamide Spectrum

5-Chloro-N-[[[4-[6-fluoro-1,4-dihydro-7-(methylamino)-2,4-dioxo-3(2H)-quinazolinyl]phenyl]amino]carbonyl]-2-thiophenesulfonamide PRT 060128 elinogrel 5-Chloro-N-[[[4-[6-fluoro-1,4-dihydro-7-(MethylaMino)-2,4-dioxo-3(2H)-quinazolinyl]phenyl]aMino]carb 2-Thiophenesulfonamide, 5-chloro-N-[[[4-[6-fluoro-1,4-dihydro-7-(methylamino)-2,4-dioxo-3(2H)-quinazolinyl]phenyl]amino]carbonyl]- P2Y Receptor,inhibit,PRT 060128,Elinogrel,Inhibitor,PRT-060128 5-Chloro-N-((4-(6-fluoro-7-(methylamino)-2,4-dioxo-1,4-dihydroquinazolin-3(2H)-yl)phenyl)carbamoyl)thiophene-2-sulfonamide 936500-94-6 C20H15ClFN5O5S2