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ChemicalBook >> CAS DataBase List >>ADRENORPHIN

ADRENORPHIN

CAS No.
88866-92-6
Chemical Name:
ADRENORPHIN
Synonyms
Metorphacid;ADRENORPHIN;METORPHAMIDE;METORPHINAMIDE;ADRENORPHIN (FREE ACID);METORPHAMIDE (FREE ACID);Adrenorphin, ≥95% (HPLC);Tyr-Gly-Gly-Phe-Arg-Arg-Val;8-L-Valineadrenorphin (human);TYR-GLY-GLY-PHE-MET-ARG-ARG-VAL
CBNumber:
CB6129590
Molecular Formula:
C44H68N14O10S
Molecular Weight:
985.16
MDL Number:
MFCD00076434
MOL File:
88866-92-6.mol
MSDS File:
SDS
Last updated:2023-05-18 11:30:59

ADRENORPHIN Properties

Density 1.42±0.1 g/cm3(Predicted)
storage temp. −20°C
solubility ≥27.75 mg/mL in H2O with ultrasonic; ≥5.64 mg/mL in EtOH with ultrasonic; ≥98.5 mg/mL in DMSO
form solid
pka 3.34±0.10(Predicted)

SAFETY

Risk and Safety Statements

WGK Germany  3

ADRENORPHIN price More Price(10)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich T8156 Adrenorphin ≥95% (HPLC) 88866-92-6 1mg $163 2022-05-15 Buy
Alfa Aesar J66389 Adrenorphin, free acid 88866-92-6 5mg $169 2021-12-16 Buy
Usbiological A0909-41A Adrenorphin, free acid 88866-92-6 1mg $531 2021-12-16 Buy
Usbiological A0909-41 Adrenorphin 88866-92-6 1mg $531 2021-12-16 Buy
Biorbyt Ltd orb364179 Adrenorphin (Free acid) > 95% 88866-92-6 5mg $552.5 2021-12-16 Buy
Product number Packaging Price Buy
T8156 1mg $163 Buy
J66389 5mg $169 Buy
A0909-41A 1mg $531 Buy
A0909-41 1mg $531 Buy
orb364179 5mg $552.5 Buy

ADRENORPHIN Chemical Properties,Uses,Production

Uses

Metorphacid Trifluoroacetate Salt is amino acid sequence; protection of endogenous therapeutic peptides from peptidase activity through conjugation to blood components.

Biological Activity

adrenorphin, also sometimes referred to as metorphamide, is an endogenous, c-terminally amidated, opioid octapeptide that is produced from proteolytic cleavage of proenkephalin a and is widely distributed throughout the mammalian brain(1). it was named based on the fact that it was originally detected in human phaeochromocytoma tumour derived from the adrenal medulla, and was subsequently found in normal human and bovine adrenal medulla as well. adrenorphin exhibits potent opioid activity, acting as a balanced μ- and κ-opioid receptor agonist while having no effects on δ-opioid receptors(2). it possesses analgesic and respiratory deppresive properties(3).figure 1 proteolytic cleavage of proenkephalin a

References

1. Matsuo H, Miyata A, Mizuno K (1983). "Novel C-terminally amidated opioid peptide in human phaeochromocytoma tumour". Nature 305 (5936): 721–3.2. Weber E, Esch FS, Böhlen P et al. (December 1983). "Metorphamide: isolation, structure, and biologic activity of an amidated opioid octapeptide from bovine brain". Proceedings of the National Academy of Sciences of the United States of America 80 (23): 7362–6.3. Xu SF, Lu WX, Zhou KR et al. (April 1985). "The analgesic and respiratory depressant actions of metorphamide in mice and rabbits". Neuropeptides 6 (2): 121–31.

ADRENORPHIN Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 74)Suppliers
Supplier Tel Email Country ProdList Advantage
Alpha Biopharmaceuticals Co., Ltd 		+86-15542445688 sales@alabiochem.com China 888 58
Shenzhen Nexconn Pharmatechs Ltd 		+86-755-89396905 +86-15013857715 admin@nexconn.com China 10310 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29815 58
Hangzhou Go Top Peptide Biotech 		0571-88211921 sales1@gotopbio.com CHINA 2609 58
Nextpeptide Inc 		+86-0571-81612335 +8613336028439 sales@nextpeptide.com China 19908 58
Alfa Chemistry 		Info@alfa-chemistry.com United States 24072 58
Chengdu Youngshe Chemical Co., Ltd. 		+8618108235634 Cecilia@youngshechem.com China 2345 58
Nanjing TGpeptide 		+86-13347807150 +86-13347807150 support@tgpeptide.com China 3279 58
Zhejiang Hangyu API Co., Ltd 		+8617531972939 anna@api-made.com China 2943 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 52925 58

View Lastest Price from ADRENORPHIN manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
ADRENORPHIN pictures 2020-02-19 ADRENORPHIN
88866-92-6
 US $7.00 / KG 1KG 99% 100kg Career Henan Chemical Co
ADRENORPHIN pictures 2020-02-19 ADRENORPHIN
88866-92-6
 US $7.00 / KG 1KG 99% 100kg Career Henan Chemical Co
  • ADRENORPHIN pictures
  • ADRENORPHIN
    88866-92-6
  • US $7.00 / KG
  • 99%
  • Career Henan Chemical Co
  • ADRENORPHIN pictures
  • ADRENORPHIN
    88866-92-6
  • US $7.00 / KG
  • 99%
  • Career Henan Chemical Co

ADRENORPHIN Spectrum

METORPHAMIDE (FREE ACID) METORPHINAMIDE METORPHAMIDE H-TYR-GLY-GLY-PHE-MET-ARG-ARG-VAL-OH ADRENORPHIN (FREE ACID) ADRENORPHIN TYR-GLY-GLY-PHE-MET-ARG-ARG-VAL 8-L-Valineadrenorphin (human) Metorphacid Tyr-Gly-Gly-Phe-Arg-Arg-Val Adrenorphin, ≥95% (HPLC) Metorphamide (free acid) H-Tyr-Gly-Gly-Phe-Met-Arg-Arg-Val-OH L-Valine, L-tyrosylglycylglycyl-L-phenylalanyl-L-methionyl-L-arginyl-L-arginyl- 88866-92-6 C44H68N14O10S Biochemicals and Reagents Amino Acids and Peptides BioChemical Peptides Other Peptides Neuroscience