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ChemicalBook >> CAS DataBase List >>2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-(2-propyn-1-yloxy)-6-quinazolinyl]-4-(dimethylamino)-, (2E)-

2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-(2-propyn-1-yloxy)-6-quinazolinyl]-4-(dimethylamino)-, (2E)-

CAS No.
1621002-27-4
Chemical Name:
2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-(2-propyn-1-yloxy)-6-quinazolinyl]-4-(dimethylamino)-, (2E)-
Synonyms
PF-06672131;PF-06672131 >=95% (HPLC);2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-(2-propyn-1-yloxy)-6-quinazolinyl]-4-(dimethylamino)-, (2E)-
CBNumber:
CB58106167
Molecular Formula:
C23H21ClFN5O2
Molecular Weight:
453.9
MDL Number:
MFCD28386021
MOL File:
1621002-27-4.mol
Last updated:2025-01-21 14:14:50

2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-(2-propyn-1-yloxy)-6-quinazolinyl]-4-(dimethylamino)-, (2E)- Properties

Boiling point 647.7±55.0 °C(Predicted)
Density 1.363±0.06 g/cm3(Predicted)
storage temp. room temp
solubility DMSO: 5mg/mL, clear (warmed)
pka 11.65±0.43(Predicted)
form powder
color white to beige

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H335-H302-H315-H319
Precautionary statements  P264-P270-P301+P312-P330-P501-P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362

2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-(2-propyn-1-yloxy)-6-quinazolinyl]-4-(dimethylamino)-, (2E)- Chemical Properties,Uses,Production

Description

PF-06672131 is a selective EGFR kinase inhibitor.

2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-(2-propyn-1-yloxy)-6-quinazolinyl]-4-(dimethylamino)-, (2E)- Preparation Products And Raw materials

Raw materials

Preparation Products

2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-(2-propyn-1-yloxy)-6-quinazolinyl]-4-(dimethylamino)-, (2E)- Suppliers

Global( 3)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+8613564774135 zijue.cai@tsbiochem.com United States 19881 58
Energy Chemical 021-58432009 400-005-6266 marketing1@energy-chemical.com China 44807 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 19699 58

View Lastest Price from 2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-(2-propyn-1-yloxy)-6-quinazolinyl]-4-(dimethylamino)-, (2E)- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
PF-06672131 pictures 2024-10-28 PF-06672131
1621002-27-4
 US $1980.00-1520.00 / mg 10g TargetMol Chemicals Inc.
  • PF-06672131 pictures
  • PF-06672131
    1621002-27-4
  • US $1980.00-1520.00 / mg
  • TargetMol Chemicals Inc.
2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-(2-propyn-1-yloxy)-6-quinazolinyl]-4-(dimethylamino)-, (2E)- PF-06672131 >=95% (HPLC) PF-06672131 1621002-27-4 C23H21ClFN5O2