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ChemicalBook >> CAS DataBase List >>Nexturastat A

Nexturastat A

CAS No.
1403783-31-2
Chemical Name:
Nexturastat A
Synonyms
CS-1289;Nexturastat A;Nextunastat A;Nexturastat A, >97%;Nexturastat A, >=98%;Nexturastat A (AG-CR1-3901);4-((1-BUTYL-3-PHENYLUREIDO)METHYL)-N-HYDROXYBENZAMIDE;4-[[butyl(phenylcarbamoyl)amino]methyl]-N-hydroxybenzamide;4-[[Butyl[(phenylamino)carbonyl]amino]methyl]-N-hydroxybenzamide;Benzamide, 4-[[butyl[(phenylamino)carbonyl]amino]methyl]-N-hydroxy-
CBNumber:
CB52715657
Molecular Formula:
C19H23N3O3
Molecular Weight:
341.4
MDL Number:
MFCD28099804
MOL File:
1403783-31-2.mol
MSDS File:
SDS
Last updated:2024-11-19 23:02:33

Nexturastat A Properties

Density 1.228±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility insoluble in H2O; ≥16.3 mg/mL in DMSO; ≥9.3 mg/mL in EtOH
form solid
pka 8.95±0.10(Predicted)
color White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338
NFPA 704
0
2 0

Nexturastat A price More Price(25)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 16874 Nexturastat A ≥95% 1403783-31-2 500μg $62 2024-03-01 Buy
Cayman Chemical 16874 Nexturastat A ≥95% 1403783-31-2 1mg $109 2024-03-01 Buy
Cayman Chemical 16874 Nexturastat A ≥95% 1403783-31-2 5mg $477 2024-03-01 Buy
Cayman Chemical 16874 Nexturastat A ≥95% 1403783-31-2 10mg $834 2024-03-01 Buy
TRC N391500 NexturastatA 1403783-31-2 25mg $1760 2021-12-16 Buy
Product number Packaging Price Buy
16874 500μg $62 Buy
16874 1mg $109 Buy
16874 5mg $477 Buy
16874 10mg $834 Buy
N391500 25mg $1760 Buy

Nexturastat A Chemical Properties,Uses,Production

Uses

Nexturastat A is a potent and selective histone deacetylase 6 (HDAC6) inhibitor that shows potential antiproliferative effects against melanoma cells.

Biological Activity

nexturastat a is a selective inhibitor of histone deacetylase 6 (hdac6) with ic50 value of 5.2 nm [1].nexturastat a is a hdac inhibitor. it was developed by structural modification of aryl urea hdacis. the inhibitory activity of nexturastat a is most potent against hdac6 with ic50 value of 5.2 nm. besides that, nexturastat a also shows inhibition of other hdacs with ic50 values of 3.02, 6.92, 6.68, 9.39, 11.7, 4.46, 0.954, 6.72, 7.57 and 5.14 μm for hdac1, 2, 3, 4, 5, 7, 8, 9, 10 and 11, respectively. nexturastat a has been shown to suppress cell proliferation and promote apoptosis in b16 murine melanoma cells [1, 2].

target

HDAC6

References

[1] kalin j h, bergman j a. development and therapeutic implications of selective histone deacetylase 6 inhibitors. journal of medicinal chemistry, 2013, 56(16): 6297-6313.
[2] zhang l, han y, jiang q, et al. trend of histone deacetylase inhibitors in cancer therapy: isoform selectivity or multitargeted strategy. medicinal research reviews, 2014.

Nexturastat A Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 97)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32957 60
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29880 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32161 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6312 58
Zhejiang J&C Biological Technology Co.,Limited 		+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10473 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6391 58
LEAP CHEM CO., LTD. 		+86-852-30606658 market18@leapchem.com China 24727 58
Coresyn Pharmatech Co., Ltd. 		+86-571-86626709 +86-18157142896 cbc@coresyn.com China 9984 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 		13417589054 trendseenbio@gmail.com China 11681 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 57505 58

View Lastest Price from Nexturastat A manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Nexturastat A pictures 2024-11-19 Nexturastat A
1403783-31-2
 US $63.00-117.00 / mg 99.57% 10g TargetMol Chemicals Inc.
4-((1-BUTYL-3-PHENYLUREIDO)METHYL)-N-HYDROXYBENZAMIDE pictures 2019-09-05 4-((1-BUTYL-3-PHENYLUREIDO)METHYL)-N-HYDROXYBENZAMIDE
1403783-31-2
 US $1.00 / ASSAYS 1ASSAYS 98% 10kg Career Henan Chemical Co
  • Nexturastat A pictures
  • Nexturastat A
    1403783-31-2
  • US $63.00-117.00 / mg
  • 99.57%
  • TargetMol Chemicals Inc.

Nexturastat A Spectrum

1403783-31-2(Nexturastat A)Related Search:

Nexturastat A, >=98% 4-[[Butyl[(phenylamino)carbonyl]amino]methyl]-N-hydroxybenzamide Nexturastat A 4-((1-BUTYL-3-PHENYLUREIDO)METHYL)-N-HYDROXYBENZAMIDE Benzamide, 4-[[butyl[(phenylamino)carbonyl]amino]methyl]-N-hydroxy- Nexturastat A 4-((1-BUTYL-3-PHENYLUREIDO)METHYL)-N-HYDROXYBENZAMIDE Nexturastat A Benzamide, 4-[[butyl[(phenylamino)carbonyl]amino]methyl]-N-hydroxy- 4-[[butyl(phenylcarbamoyl)amino]methyl]-N-hydroxybenzamide CS-1289 Nexturastat A, >97% Nextunastat A Nexturastat A (AG-CR1-3901) 1403783-31-2 Inhibitors