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ChemicalBook >> CAS DataBase List >>Teriflunomide Impurity 3

Teriflunomide Impurity 3

CAS No.
62004-05-1
Chemical Name:
Teriflunomide Impurity 3
Synonyms
Leflunomide Impurity 3;Teriflunomide impurities;Teriflunomide-3-isomer/ 3-Trifluoro Isomer;2-Butenamide, 2-cyano-3-hydroxy-N-[3-(trifluoromethyl)phenyl]-
CBNumber:
CB44800792
Molecular Formula:
C12H9F3N2O2
Molecular Weight:
270.21
MDL Number:
MOL File:
62004-05-1.mol
MSDS File:
SDS

Teriflunomide Impurity 3 Properties

Boiling point 405.5±45.0 °C(Predicted)
Density 1.424±0.06 g/cm3(Predicted)
pka 5.20±0.50(Predicted)

Teriflunomide Impurity 3 Chemical Properties,Uses,Production

Uses

2-Cyano-3-hydroxy-N-[3-(trifluoromethyl)phenyl]-2-butenamide is a derivative of Leflunomide(L322750) which is an immunosuppressive. Inhibits T and B cell proliferation. Activity is attributed mainly to its metabolite, a malononitrile derivative, which is beleived to inhibit dihydroorotate dehydrogenase as well as several protein tyrosine kinases. Therapeutically as a antirheumatic (Merck Index).This compound is suitable for dihydroorotate dehydrogenase (DHODH) related research.

Teriflunomide Impurity 3 Preparation Products And Raw materials

Raw materials

Preparation Products

Teriflunomide Impurity 3 Suppliers

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Leflunomide Impurity 3 2-Butenamide, 2-cyano-3-hydroxy-N-[3-(trifluoromethyl)phenyl]- Teriflunomide-3-isomer/ 3-Trifluoro Isomer Teriflunomide impurities 62004-05-1