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ChemicalBook >> CAS DataBase List >>aureothricin

aureothricin

CAS No.
574-95-8
Chemical Name:
aureothricin
Synonyms
Propionylpyrrothione, Farcinin;5-Methyl-3-propionamidopyrrolin-4-one-[4,3-d]-1,2-dithiole;N-(4,5-Dihydro-4-methyl-5-oxo-1,2-dithiolo[4,3-b]pyrrol-6-yl)propanamide;N-(4,5-Dihydro-4-methyl-5-oxo-1,2-dithiolo[4,3-b]pyrrol-6-yl)propionamide;Propanamide, N-(4,5-dihydro-4-methyl-5-oxo-1,2-dithiolo[4,3-b]pyrrol-6-yl)-;Propionopyrrothine, 5-Methyl-3-propionamidopyrrolin-4-one[4,3-d]-1,2-dithiole
CBNumber:
CB41334476
Molecular Formula:
C9H10N2O2S2
Molecular Weight:
242.32
MDL Number:
MFCD07370147
MOL File:
574-95-8.mol
MSDS File:
SDS
Last updated:2024-10-23 13:36:13

aureothricin Properties

Melting point 260-270℃ (decomposition)
Boiling point 479.1±45.0 °C(Predicted)
Density 1.48±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: soluble; DMSO: soluble; Ethanol: partially soluble; Methanol: partially soluble
pka 10.54±0.20(Predicted)
form Yellow to orange solid.
color Yellow
FDA UNII 0KX00L19Q2

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS06
Signal word  Danger
Hazard statements  H301+H311+H331
Precautionary statements  P280
HS Code  29419090
NFPA 704
0
4 0

aureothricin price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 19942 Aureothricin ≥98% 574-95-8 500μg $141 2024-03-01 Buy
Cayman Chemical 19942 Aureothricin ≥98% 574-95-8 1mg $239 2024-03-01 Buy
Cayman Chemical 19942 Aureothricin ≥98% 574-95-8 5mg $769 2024-03-01 Buy
TRC A794573 Aureothricin 574-95-8 1mg $1000 2021-12-16 Buy
TRC A794573 Aureothricin 574-95-8 0.5mg $525 2021-12-16 Buy
Product number Packaging Price Buy
19942 500μg $141 Buy
19942 1mg $239 Buy
19942 5mg $769 Buy
A794573 1mg $1000 Buy
A794573 0.5mg $525 Buy

aureothricin Chemical Properties,Uses,Production

Uses

Aureothricin is an antibiotic first described by Umezawa and co-workers in Japan in 1949. Resurgent interest in this class of microbial metabolites was stimulated by the discovery of their selective antitumour activity. Aureothricin is a more hydrophobic analogue of thiolutin, but has received only limited attention. Members of this class, notably thiolutin, are potent inhibitors of bacterial and yeast RNA polymerases, inhibitors of mannan and glucan formation in fungi, and inhibitors of tumour-cell induced angiogenesis in vivo.

Definition

ChEBI: Aureothricin is a dithiolopyrrolone antibiotic that is 4,5-dihydro[1,2]dithiolo[4,3-b]pyrrole in which the hydrogens at positions 4,5 and 6 have been replaced by methyl, oxo and propanoylamino groups, respectively. It is a moderate antimicrobial by-product of the thiolutin fermentation in various Streptomyces species. It has a role as a bacterial metabolite, an angiogenesis inhibitor, an antibacterial agent and an EC 2.7.7.6 (RNA polymerase) inhibitor. It is a dithiolopyrrolone antibiotic and a secondary carboxamide.

storage

+4°C

aureothricin Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 34)Suppliers
Supplier Tel Email Country ProdList Advantage
Shaanxi Dideu Medichem Co. Ltd
+86-29-87569266 15319487004 1015@dideu.com China 3942 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32161 58
BOC Sciences
16314854226; +16314854226 inquiry@bocsci.com United States 19741 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38631 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
Sichuan Wei Keqi Biological Technology Co., Ltd. 028-81700200 18116577057 3003855609@qq.com China 7887 56
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9806 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 18892239720 psaitong@jm-bio.com China 12306 58
Lynnchem 86-(0)29-85992781 17792393971 info@lynnchem.com China 4587 58
Novachemistry 44-20819178-90 02081917890 info@novachemistry.com United Kingdom 4381 58

View Lastest Price from aureothricin manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Aureothricin pictures 2024-10-24 Aureothricin
574-95-8
US $598.00 / mg 10g TargetMol Chemicals Inc.

574-95-8(aureothricin)Related Search:

N-(4,5-Dihydro-4-methyl-5-oxo-1,2-dithiolo[4,3-b]pyrrol-6-yl)propanamide N-(4,5-Dihydro-4-methyl-5-oxo-1,2-dithiolo[4,3-b]pyrrol-6-yl)propionamide Propionopyrrothine, 5-Methyl-3-propionamidopyrrolin-4-one[4,3-d]-1,2-dithiole Propionylpyrrothione, Farcinin 5-Methyl-3-propionamidopyrrolin-4-one-[4,3-d]-1,2-dithiole Propanamide, N-(4,5-dihydro-4-methyl-5-oxo-1,2-dithiolo[4,3-b]pyrrol-6-yl)- 574-95-8 antibiotic