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ChemicalBook >> CAS DataBase List >>Ginsenoside Rh2

Ginsenoside Rh2

CAS No.
78214-33-2
Chemical Name:
Ginsenoside Rh2
Synonyms
20(S)-Rh2;GINSENOSIDE RH2;Ginsenoside Rh2-RM;Ginsenoside Rh2(P);GINSENOSIDE Rh2(SH);Ginsenoside Rh2(AS);Ginsenoside Rh2 ,98%;3β-(β-D-Glucopyranosyl;R-form-Ginsenoside Rh2;Ginsenoside Rh2, 20(S)-
CBNumber:
CB3728899
Molecular Formula:
C36H62O8
Molecular Weight:
622.88
MDL Number:
MFCD00800712
MOL File:
78214-33-2.mol
Last updated:2024-10-28 23:16:16

Ginsenoside Rh2 Properties

Melting point 139-144 °C
Boiling point 726.4±60.0 °C(Predicted)
Density 1.19±0.1 g/cm3(Predicted)
storage temp. Inert atmosphere,2-8°C
solubility DMF: 10 mg/ml; DMSO: 10 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml
form Solid
pka 12.91±0.70(Predicted)
color White
InChIKey CKUVNOCSBYYHIS-IRFFNABBSA-N
LogP 5.620 (est)
CAS DataBase Reference 78214-33-2(CAS DataBase Reference)
FDA UNII 0JU44A5KWG

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338
Hazard Codes  Xn
Risk Statements  22
Safety Statements  24/25
WGK Germany  3
RTECS  LZ5776539
HS Code  29389090
NFPA 704
0
2 0

Ginsenoside Rh2 price More Price(50)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 73658 Ginsenoside Rh2 analytical standard 78214-33-2 10mg $714 2024-03-01 Buy
Cayman Chemical 23390 Ginsenoside Rh2 ≥98% 78214-33-2 1mg $49 2024-03-01 Buy
Cayman Chemical 23390 Ginsenoside Rh2 ≥98% 78214-33-2 5mg $190 2024-03-01 Buy
Cayman Chemical 23390 Ginsenoside Rh2 ≥98% 78214-33-2 10mg $286 2024-03-01 Buy
Cayman Chemical 23390 Ginsenoside Rh2 ≥98% 78214-33-2 25mg $651 2024-03-01 Buy
Product number Packaging Price Buy
73658 10mg $714 Buy
23390 1mg $49 Buy
23390 5mg $190 Buy
23390 10mg $286 Buy
23390 25mg $651 Buy

Ginsenoside Rh2 Chemical Properties,Uses,Production

Description

Ginsenoside Rh2 is a steroid glycoside found in plants of the genus Panax that has diverse biological activities. It inhibits release of β-hexosaminidase from RBL-2H3 cells (IC50 = 100 μM) and inhibits the IgE-dependent passive cutaneous anaphylaxis reaction in mice at a dose of 25 mg/kg. It inhibits growth of HRA ovarian and BxPC-3 pancreatic cancer cells in a dose-dependent manner. In vivo, ginsenoside Rh2 decreases immobility time in the forced swim test in a mouse model of colorectal carcinoma. Ginsenoside Rh2 also reduces infarct volume in a rat model of ischemia-reperfusion-induced brain injury.

Chemical Properties

White solid

Uses

20(S)-Ginsenoside Rh2 is a bioactive metabolite of the ginsenoside component of Panax ginseng that has been shown to exhibit antibacterial effects in vitro.

Definition

ChEBI: A ginsenoside found in Panax species that is dammarane which is substituted by hydroxy groups at the 3beta, 12beta and 20 pro-S positions, in which the hydroxy group at position 3 has been converted to the corresponding beta-D-glucopyranoside, and in which a double bond has been introduced at the 24-25 position.

Biological Activity

Ginsenoside-Rh2, a plant glycosidewith a dammarane skeleton, has been shown to induce apoptosis in a caspase 3,8-dependent manner or the activation of cyclinA-Cdk2 by caspase 3-mediated cleavage of p21(WAF1/CIP1). Also, ginsenoside-Rh2 was shown to inhibit proliferation by inducing the protein expression of p21 and reducing the protein levels of cyclin D, which resulted in the downregulation of cyclin/Cdk complex kinase activity, a reduction in phosphorylation of pRb and the inhibition of E2F release or modulation of MAP kinases in various cancer cells[1].

Ginsenoside Rh2 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 268)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei baicao biology science and technology co., ltd
+86-19131911055 +8617824879454 zhang@hbbocao.com China 1029 58
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd
+86-18791163155 +86-13119157289 13119157289@163.com China 2971 58
Chengdu Biopurify Phytochemicals Ltd.
+8618080483897 sales@biopurify.com China 3772 58
Zibo Hangyu Biotechnology Development Co., Ltd 		+86-0533-2185556 +8617865335152 Mandy@hangyubiotech.com China 10986 58
Shanghai Zheyan Biotech Co., Ltd. 		18017610038 zheyansh@163.com CHINA 3619 58
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29886 58
Nanjing Dolon Biotechnology Co.,Ltd. 		18905173768 sales@dolonchem.com CHINA 2972 58
NanJing Spring & Autumn Biological Engineering CO., LTD. 		+8613815430202 sale02@cqherb.com CHINA 376 58
Hubei xin bonus chemical co. LTD 		86-13657291602 linda@hubeijusheng.com CHINA 22963 58
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19553 58

Related articles

View Lastest Price from Ginsenoside Rh2 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Ginsenoside Rh2 pictures 2024-10-30 Ginsenoside Rh2
78214-33-2
 US $0.00 / g 1g ≥98% HPLC 1000kg Changsha Staherb Natural Ingredients Co., Ltd.
Ginsenoside Rh2 pictures 2024-10-28 Ginsenoside Rh2
78214-33-2
 US $32.00-68.00 / mg 99.76% 10g TargetMol Chemicals Inc.
Ginsenoside Rh2 pictures 2024-08-27 Ginsenoside Rh2
78214-33-2
 US $100.00-1000.00 / KG 1KG 0.99 20 tons Zibo Hangyu Biotechnology Development Co., Ltd
  • Ginsenoside Rh2 pictures
  • Ginsenoside Rh2
    78214-33-2
  • US $0.00 / g
  • ≥98% HPLC
  • Changsha Staherb Natural Ingredients Co., Ltd.
  • Ginsenoside Rh2 pictures
  • Ginsenoside Rh2
    78214-33-2
  • US $32.00-68.00 / mg
  • 99.76%
  • TargetMol Chemicals Inc.
  • Ginsenoside Rh2 pictures
  • Ginsenoside Rh2
    78214-33-2
  • US $100.00-1000.00 / KG
  • 0.99
  • Zibo Hangyu Biotechnology Development Co., Ltd
b-D-Glucopyranoside, (3b,12b)-12,20-dihydroxydaMMar-24-en-3-yl (3β,12β)-12,20-Dihydroxydammar-24-en-3-yl-β-D-glucopyranoside Ginsenoside Rh2, 20(S)- (3beta,12beta)-12,20-dihydroxydammar-24-en-3-yl beta-d-glucopyranoside GINSENOSIDE RH2 dihydroxydammar-24-en-3-yl β-D-Glucopyranoside, (3β,12β)-12,20- R-form-Ginsenoside Rh2 12β,20-Dihydroxy-5α-dammar-24-en-3β-yl β-D-glucopyranoside 3β-(β-D-Glucopyranosyloxy)dammara-24-ene-12β,20-diol 3β-(β-D-Glucopyranosyl GINSENOSIDE Rh2(SH) Ginsenoside Rh2 ,98% 20(S)-Rh2 Natural Plant Extracts Ginsenoside Rh2 HPLC 15% 50% 98% 78214-33-2 2-[[12-hydroxy-17-(2-hydroxy-6-methylhept-5-en-2-yl)-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol β-D-Glucopyranoside, (3β,12β)-12,20-dihydroxydammar-24-en-3-yl Ginsenoside Rh2 USP/EP/BP (2R,3R,4S,5S,6R)-2-[[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-17-[(2S)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol Ginsenoside Rk1&Rh2&Rg3 GINSENOSIDE Rh2 (S-FORM)(AS) 25mg Ginsenoside Rh2-RM Ginsenoside Rh2(AS) Ginsenoside Rh2(P) 78214-33-2 C36H62O8 chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract Inhibitors Ginsenoside series 78214-33-2