Ginsenoside Rh2
- CAS No.
- 78214-33-2
- Chemical Name:
- Ginsenoside Rh2
- Synonyms
- 20(S)-Rh2;GINSENOSIDE RH2;Ginsenoside Rh2-RM;Ginsenoside Rh2(P);GINSENOSIDE Rh2(SH);Ginsenoside Rh2(AS);Ginsenoside Rh2 ,98%;3β-(β-D-Glucopyranosyl;R-form-Ginsenoside Rh2;Ginsenoside Rh2, 20(S)-
- CBNumber:
- CB3728899
- Molecular Formula:
- C36H62O8
- Molecular Weight:
- 622.88
- MDL Number:
- MFCD00800712
- MOL File:
- 78214-33-2.mol
Melting point | 139-144 °C |
---|---|
Boiling point | 726.4±60.0 °C(Predicted) |
Density | 1.19±0.1 g/cm3(Predicted) |
storage temp. | Inert atmosphere,2-8°C |
solubility | DMF: 10 mg/ml; DMSO: 10 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml |
form | Solid |
pka | 12.91±0.70(Predicted) |
color | White |
InChIKey | CKUVNOCSBYYHIS-IRFFNABBSA-N |
LogP | 5.620 (est) |
CAS DataBase Reference | 78214-33-2(CAS DataBase Reference) |
FDA UNII | 0JU44A5KWG |
Ginsenoside Rh2 price More Price(50)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 73658 | Ginsenoside Rh2 analytical standard | 78214-33-2 | 10mg | $714 | 2024-03-01 | Buy |
Cayman Chemical | 23390 | Ginsenoside Rh2 ≥98% | 78214-33-2 | 1mg | $49 | 2024-03-01 | Buy |
Cayman Chemical | 23390 | Ginsenoside Rh2 ≥98% | 78214-33-2 | 5mg | $190 | 2024-03-01 | Buy |
Cayman Chemical | 23390 | Ginsenoside Rh2 ≥98% | 78214-33-2 | 10mg | $286 | 2024-03-01 | Buy |
Cayman Chemical | 23390 | Ginsenoside Rh2 ≥98% | 78214-33-2 | 25mg | $651 | 2024-03-01 | Buy |
Ginsenoside Rh2 Chemical Properties,Uses,Production
Description
Ginsenoside Rh2 is a steroid glycoside found in plants of the genus Panax that has diverse biological activities. It inhibits release of β-hexosaminidase from RBL-2H3 cells (IC50 = 100 μM) and inhibits the IgE-dependent passive cutaneous anaphylaxis reaction in mice at a dose of 25 mg/kg. It inhibits growth of HRA ovarian and BxPC-3 pancreatic cancer cells in a dose-dependent manner. In vivo, ginsenoside Rh2 decreases immobility time in the forced swim test in a mouse model of colorectal carcinoma. Ginsenoside Rh2 also reduces infarct volume in a rat model of ischemia-reperfusion-induced brain injury.
Chemical Properties
White solid
Uses
20(S)-Ginsenoside Rh2 is a bioactive metabolite of the ginsenoside component of Panax ginseng that has been shown to exhibit antibacterial effects in vitro.
Definition
ChEBI: A ginsenoside found in Panax species that is dammarane which is substituted by hydroxy groups at the 3beta, 12beta and 20 pro-S positions, in which the hydroxy group at position 3 has been converted to the corresponding beta-D-glucopyranoside, and in which a double bond has been introduced at the 24-25 position.
Biological Activity
Ginsenoside-Rh2, a plant glycosidewith a dammarane skeleton, has been shown to induce apoptosis in a caspase 3,8-dependent manner or the activation of cyclinA-Cdk2 by caspase 3-mediated cleavage of p21(WAF1/CIP1). Also, ginsenoside-Rh2 was shown to inhibit proliferation by inducing the protein expression of p21 and reducing the protein levels of cyclin D, which resulted in the downregulation of cyclin/Cdk complex kinase activity, a reduction in phosphorylation of pRb and the inhibition of E2F release or modulation of MAP kinases in various cancer cells[1].
Ginsenoside Rh2 Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hebei baicao biology science and technology co., ltd | +86-19131911055 +8617824879454 | zhang@hbbocao.com | China | 1029 | 58 |
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd | +86-18791163155 +86-13119157289 | 13119157289@163.com | China | 2971 | 58 |
Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3772 | 58 |
Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 | Mandy@hangyubiotech.com | China | 10986 | 58 |
Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29886 | 58 |
Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | sales@dolonchem.com | CHINA | 2972 | 58 |
NanJing Spring & Autumn Biological Engineering CO., LTD. | +8613815430202 | sale02@cqherb.com | CHINA | 376 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
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- Aug 14,2024
View Lastest Price from Ginsenoside Rh2 manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-10-30 | Ginsenoside Rh2
78214-33-2
|
US $0.00 / g | 1g | ≥98% HPLC | 1000kg | Changsha Staherb Natural Ingredients Co., Ltd. | ||
2024-10-28 | Ginsenoside Rh2
78214-33-2
|
US $32.00-68.00 / mg | 99.76% | 10g | TargetMol Chemicals Inc. | |||
2024-08-27 | Ginsenoside Rh2
78214-33-2
|
US $100.00-1000.00 / KG | 1KG | 0.99 | 20 tons | Zibo Hangyu Biotechnology Development Co., Ltd |
- Ginsenoside Rh2
78214-33-2
- US $0.00 / g
- ≥98% HPLC
- Changsha Staherb Natural Ingredients Co., Ltd.
- Ginsenoside Rh2
78214-33-2
- US $32.00-68.00 / mg
- 99.76%
- TargetMol Chemicals Inc.
- Ginsenoside Rh2
78214-33-2
- US $100.00-1000.00 / KG
- 0.99
- Zibo Hangyu Biotechnology Development Co., Ltd