ChemicalBook >> CAS DataBase List >>CAY10726
CAY10726
- CAS No.
- 1611446-66-2
- Chemical Name:
- CAY10726
- Synonyms
- CAY10726;16-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-hexadecanoicacid;Hexadecanoic acid, 16-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-
- CBNumber:
- CB34666984
- Molecular Formula:
- C24H36ClF3N2O3
- Molecular Weight:
- 493
- MDL Number:
- MOL File:
- 1611446-66-2.mol
Last updated:2024-10-28 23:16:16
CAY10726 price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 23859 | CAY10726 ≥98% | 1611446-66-2 | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 23859 | CAY10726 ≥98% | 1611446-66-2 | 5mg | $139 | 2024-03-01 | Buy |
| Cayman Chemical | 23859 | CAY10726 ≥98% | 1611446-66-2 | 10mg | $243 | 2024-03-01 | Buy |
| Cayman Chemical | 23859 | CAY10726 ≥98% | 1611446-66-2 | 25mg | $533 | 2024-03-01 | Buy |
| AK Scientific | 8471DW | 16-[[4-Chloro-3-(trifluoromethyl)phenyl]carbamoylamino]hexadecanoicacid | 1611446-66-2 | 5mg | $252 | 2021-12-16 | Buy |
CAY10726 Chemical Properties,Uses,Production
Description
CAY10726 is an arylurea fatty acid.1 It decreases ATP production by 28% in MDA-MB-231 breast cancer cells when used at a concentration of 10 μM. CAY10726 decreases proliferation and initiates apoptosis in MDA-MB-231 cells via depletion of the phospholipid cardiolipin and its precursor phosphatidylglycerol from the mitochondrial membrane. In vivo, CAY10726 (2.5-40 mg/kg) reduces tumor volume and increases tumor cell apoptosis in a mouse MDA-MB-231 breast cancer xenograft model in a dose-dependent manner.
References
1. Rawling, T., Choucair, H., Koolaji, N., et al. A novel arylurea fatty acid that targets the mitochondrion and depletes cardiolipin to promote killing of breast cancer cells J. Med. Chem. 60(20),8661-8666(2017).
CAY10726 Preparation Products And Raw materials
Raw materials
Preparation Products
CAY10726 Suppliers
Global( 6)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32161 | 58 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6777 | 58 |
| Shanghai Yiyan Biotechnology Co. , Ltd. | 021-69985186 13611928337 | 3427709316@qq.com | China | 7978 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11974 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 19703 | 58 |
CAY10726
Hexadecanoic acid, 16-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-
16-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-hexadecanoicacid
1611446-66-2
C24H36ClF3N2O3