CAIX Inhibitor S4
- CAS No.
- 1330061-67-0
- Chemical Name:
- CAIX Inhibitor S4
- Synonyms
- S4 >=98% (HPLC);CAIX Inhibitor S4;CAIX Inhibitor S4, 10 mM in DMSO;4-(3-(3,5-Dimethylphenyl)ureido)phenyl sulfamate;4-[[[(3,5-Dimethylphenyl)amino]carbonyl]amino]phenyl sulfamate;Sulfamic acid, 4-[[[(3,5-dimethylphenyl)amino]carbonyl]amino]phenyl ester
- CBNumber:
- CB33309354
- Molecular Formula:
- C15H17N3O4S
- Molecular Weight:
- 335.38
- MDL Number:
- MFCD30182321
- MOL File:
- 1330061-67-0.mol
CAIX Inhibitor S4 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML2031 | S4 ≥98% (HPLC) | 1330061-67-0 | 5MG | $105 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML2031 | S4 ≥98% (HPLC) | 1330061-67-0 | 25MG | $424 | 2024-03-01 | Buy |
| TRC | S019995 | S4 | 1330061-67-0 | 50mg | $470 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0009832 | S-4 95.00% | 1330061-67-0 | 5MG | $455.08 | 2021-12-16 | Buy |
| AK Scientific | 6486DK | 4-[(3,5-Dimethylphenyl)Ureido]PhenylSulfamate | 1330061-67-0 | 5mg | $187 | 2021-12-16 | Buy |
CAIX Inhibitor S4 Chemical Properties,Uses,Production
Uses
S4 is a sulfamate carbonic anhydrase IX (CAIX) inhibitor in colorectal carcinoma cell lines.
Biological Activity
S4 is a potent and selective inhibitor against sulfamate carbonic anhydrase (CA) subtypes CAIX & CAXII (Ki = 2, 7, 546, 5600 nM against human CA XII, IX, II, and I, respectively). S4 selectively inhibits migration upon anoxia/hypoxia-induced CAIX expression in cancer cultures (% inhibition/conc./cell line = 54%/100 μM/WRO, 65%/33 μM/MDA-MB-231), while exhibiting no inhibitory effects under normoxia or among non-CAIX-expressing cells (HCT116 & RT112). Daily intraperitoneal injection (10 mg/kg) is reported to reduce the metastatic tumor burden in lungs of mice bearing orthotopic eGFP-MDA-MB-231 tumors in vivo.
storage
Store at +4°C
CAIX Inhibitor S4 Preparation Products And Raw materials
Raw materials
Preparation Products
CAIX Inhibitor S4 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| hebei hongtan Biotechnology Co., Ltd | +852-6619 3215 +86-17731935328 | sales03@chemcn.cn | China | 970 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21631 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32159 | 58 |
| Hangzhou Huarong Pharm Co., Ltd. | 571-86758373 +8613588754946 | sales@huarongpharm.com | CHINA | 3148 | 58 |
| Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | sales@chemhifuture.com | China | 3135 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38630 | 58 | |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8467 | 58 |
| Wuhan Quanjinci New Material Co.,Ltd. | +86-15271838296; +8615271838296 | kyra@quanjinci.com | China | 1512 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43340 | 58 |
View Lastest Price from CAIX Inhibitor S4 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-03-04 | S4
1330061-67-0
|
US $30.00 / g | 10g | 98% | 2000kg | hebei hongtan Biotechnology Co., Ltd | |
 |
2024-11-19 | CAIX Inhibitor S4
1330061-67-0
|
US $34.00-97.00 / mg | 98.35% | 10g | TargetMol Chemicals Inc. | ||
 |
2024-09-29 | S4
1330061-67-0
|
US $1.00 / g | 1g | 99 | 20tons | Shanghai Longyu Biotechnology Co., Ltd. |
-
- S4
1330061-67-0
- US $30.00 / g
- 98%
- hebei hongtan Biotechnology Co., Ltd
-
- CAIX Inhibitor S4
1330061-67-0
- US $34.00-97.00 / mg
- 98.35%
- TargetMol Chemicals Inc.
-
- S4
1330061-67-0
- US $1.00 / g
- 99
- Shanghai Longyu Biotechnology Co., Ltd.