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ChemicalBook >> CAS DataBase List >>IL-17A inhibitor 1

IL-17A inhibitor 1

CAS No.
2452464-73-0
Chemical Name:
IL-17A inhibitor 1
Synonyms
LY-3533028;IL-17A inhibitor 1;inhibit,Inhibitor,Interleukin Related,COPD,Asthma,IL-17A inhibitor 1,IL17A inhibitor 1,IL 17A inhibitor 1;1,2,5-Oxadiazole-3-carboxamide, N-[(S)-(4,4-difluorocyclohexyl)[7-[(1S)-2-methoxy-1-[(4S)-2-oxo-4-(trifluoromethyl)-1-imidazolidinyl]ethyl]imidazo[1,2-b]pyridazin-2-yl]methyl]-4-methyl-
CBNumber:
CB28529477
Molecular Formula:
C24H27F5N8O4
Molecular Weight:
586.51
MDL Number:
MFCD34474218
MOL File:
2452464-73-0.mol
Last updated:2024-10-31 13:32:20

IL-17A inhibitor 1 Properties

Density 1?+-.0.1 g/cm3(Predicted)
storage temp. Store at -20°C
pka 11.52±0.46(Predicted)
form Solid
color Off-white to yellow

IL-17A inhibitor 1 Chemical Properties,Uses,Production

Biological Activity

IL-17A inhibitor 1 (example 24) is a IL-17A inhibitor, with IC50 values of <9.45 nM and 9.3 nM in alphalisa assay and HT-29 cells[1]. IL-17A inhibitor 1 (example 24) possesses high oral bioavailability (F=107%)[1].

References

[1]. COATES DAVID ANDREW, et al. IMIDAZO[1,2-B]PYRIDAZINE IL-17A INHIBITORS. Patent WO2020146194.

IL-17A inhibitor 1 Preparation Products And Raw materials

Raw materials

Preparation Products

IL-17A inhibitor 1 Suppliers

Global( 19)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
support@targetmol.com United States 38460 58
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 52925 58
Wuhan Jingkang en Biomedical Technology Co., Ltd
+8613720134139 orders@jknbiochem.com China 5221 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24649 58
Chuzhou KeMail Chemical Technology Co., Ltd 0550-5196001 15000891977 wj520wjxby@126.com China 1841 55
ShangHai Angti Biotechnology Co., Ltd. 13764913901 info@angtibio.com China 4989 55
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9806 58
Shanghai Rechem science Co., Ltd. 21-31433387 15618786686 sales@rechemscience.com China 2981 58
Kaixin Chemical (Hong Kong) Limited 010-88886666-01 13112345678 loyson@tcypharm.com China 595 55
Chunchuang (Wuhan) Technology Co., Ltd 15342225168 yutianchun2007@126.com China 9999 58
1,2,5-Oxadiazole-3-carboxamide, N-[(S)-(4,4-difluorocyclohexyl)[7-[(1S)-2-methoxy-1-[(4S)-2-oxo-4-(trifluoromethyl)-1-imidazolidinyl]ethyl]imidazo[1,2-b]pyridazin-2-yl]methyl]-4-methyl- LY-3533028 IL-17A inhibitor 1 inhibit,Inhibitor,Interleukin Related,COPD,Asthma,IL-17A inhibitor 1,IL17A inhibitor 1,IL 17A inhibitor 1 2452464-73-0 C24H27F5N8O4