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ChemicalBook >> CAS DataBase List >>Faropenem sodium hemipentahydrate

Faropenem sodium hemipentahydrate

CAS No.
106560-14-9
Chemical Name:
Faropenem sodium hemipentahydrate
Synonyms
FROPENEM;FAROPENEM;Faropenem Sodium Impurity G;Faropenem sodium hemi 5-hydrate;Faropenem sodium hemipentahydrate;Faropenem sodium hemipentahydrate USP/EP/BP;6α-[(R)-1-hydroxyethyl]-2-[(R)-tetrahydrofuran-2-yl]pen-2-em-3-carboxylic acid;(5R,6S,8R,2'R)-2-(2'-tetrahydrofuryl)-6-(1-hydroxyethyl)-2-penem-3-carboxylic acid;6alpha-[(R)-1-hydroxyethyl]-2-[(R)-tetrahydrofuran-2-yl]pen-2-em-3-carboxylic acid;(5R,6S)-6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(2R)-2-oxolanyl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
CBNumber:
CB1300660
Molecular Formula:
C12H15NO5S
Molecular Weight:
285.32
MDL Number:
MFCD00868867
MOL File:
106560-14-9.mol
Last updated:2023-05-04 17:34:31

Faropenem sodium hemipentahydrate Properties

Boiling point 570.2±50.0 °C(Predicted)
Density 1.56±0.1 g/cm3(Predicted)
pka 4.00±0.40(Predicted)
CAS DataBase Reference 106560-14-9
FDA UNII F52Y83BGH3
ATC code J01DI03

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338

Faropenem sodium hemipentahydrate price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC F103303 Faropenem 106560-14-9 100mg $580 2021-12-16 Buy
American Custom Chemicals Corporation API0002771 FROPENEM 95.00% 106560-14-9 5G $927.76 2021-12-16 Buy
AHH API-1035 Fropenem 98% 106560-14-9 100mg $600 2021-12-16 Buy
AvaChem 1723A Faropenem 106560-14-9 10mg $39 2021-12-16 Buy
AvaChem 1723A Faropenem 106560-14-9 100mg $89 2021-12-16 Buy
Product number Packaging Price Buy
F103303 100mg $580 Buy
API0002771 5G $927.76 Buy
API-1035 100mg $600 Buy
1723A 10mg $39 Buy
1723A 100mg $89 Buy

Faropenem sodium hemipentahydrate Chemical Properties,Uses,Production

Description

Farom was launched in Japan for use as an antibiotic against common respiratory tract pathogens. It can be prepared by several related routes of about seven steps starting with tetrahydrofuran-2-thiocarboxylic acid and a silylated azetidinone. It is a broad spectrum oral penem antibiotic that is β-lactamase stable. Farom is the most active β-lactam against anaerobes (more than cefaclor, cefixime and amoxicillin) but also has activity against Gram-positive, Gram-negative and enterobacteriaceae. It is equally active against strains carrying plasmid and chromosome mediated β-lactamases. The short plasma elimination half-life is the result of hydrolysis by renal dehydropeptidase. It is more stable to hydrolysis by extended spectrum β-lactamases than some second and third generation cephalosporins.

Originator

Suntory (Japan)

Uses

Treatmentof bacterial infections.

Uses

Faropenem (cas# 106560-14-9) is a compound useful in organic synthesis.

Definition

ChEBI: 6alpha-[(R)-1-hydroxyethyl]-2-[(R)-tetrahydrofuran-2-yl]pen-2-em-3-carboxylic acid is a faropenem. It is a conjugate acid of a 6alpha-[(R)-1-hydroxyethyl]-2-[(R)-tetrahydrofuran-2-yl]pen-2-em-3-carboxylate.

brand name

Farom

Antimicrobial activity

An orally active penem with a broad spectrum of antibacterial activity, including activity against selected anaerobic pathogens. Although it is active against most enterobacteria, it has reduced activity against Ser. marcescens, Enterobacter spp. and some Providencia spp. It generally retains activity against many Gram-positive organisms, but has no useful activity against Ps. aeruginosa. It has reduced activity against E. faecium, methicillin-resistant Staph. aureus (MRSA) and some strains of coagulase-negative staphylococci. It is stable to hydrolysis by extended spectrum β-lactamases, but is hydrolyzed by carbapenemases. Esterified prodrugs with increased bioavailability have been studied in clinical trials but have not received regulatory approval.

Faropenem sodium hemipentahydrate Preparation Products And Raw materials

Global( 134)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21634 55
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29880 58
Xiamen AmoyChem Co., Ltd 		+86-86-5926051114 +8618959220845 sales@amoychem.com China 6383 58
Chongqing Chemdad Co., Ltd 		+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39894 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49374 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		+8613580539051 joe@yuhengpharm.com CHINA 21142 58
SIMAGCHEM CORP 		+86-13806087780 sale@simagchem.com China 17365 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6312 58
Shaanxi Dideu Medichem Co. Ltd 		+86-029-89586680 +86-18192503167 1026@dideu.com China 7724 58
AFINE CHEMICALS LIMITED 		+86-0571-85134551 sales@afinechem.com China 15352 58

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View Lastest Price from Faropenem sodium hemipentahydrate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Faropenem Sodium Hydrate pictures 2024-04-10 Faropenem Sodium Hydrate
106560-14-9
 US $0.00-0.00 / mg 10mg 90%+ 10g Guangzhou PI PI BIOTECH INC
Faropenem sodium hemipentahydrate pictures 2019-07-06 Faropenem sodium hemipentahydrate
106560-14-9
 US $7.00 / kg 1kg 99% 100KG Career Henan Chemical Co
[5R-[3(R^<*>^)，5α，6α(R^<*>^)]]-6-(1-hydroxyethyl)-7-oxo-3-(tetrahydro-2-furanyl)-4-thia-1-azobicyclo[3.2.0]leapt-2- ene-2-carboxylicacid (5R,6S)-6-[(1R)-1-hydroxyethyl]-7-keto-3-[(2R)-tetrahydrofuran-2-yl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid (5R,6S)-6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(2R)-oxolan-2-yl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid 6alpha-[(R)-1-hydroxyethyl]-2-[(R)-tetrahydrofuran-2-yl]pen-2-em-3-carboxylic acid (+)-(5R,6S)-6-[(1R)-1-Hydroxyethyl]-7-oxo-3-[(2R)-tetrahydro-2-furyl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid (5R,6S,8R,2'R)-2-(2'-tetrahydrofuryl)-6-(1-hydroxyethyl)-2-penem-3-carboxylic acid 4-Thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 6-(1-hydroxyethyl)-7-oxo-3-(tetrahydro-2-furanyl)-, [5R-[3(R*),5α,6α(R*)]]- 4-Thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(2R)-tetrahydro-2-furanyl]-, (5R,6S)- 6-[(1R)-1-Hydroxyethyl]-7-oxo-3-[(2R)-tetrahydro-2-furanyl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid monosodium salt hemipentahydrate Faropenem sodium hemipentahydrate FAROPENEM FROPENEM (5R,6R)-6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(2R)-tetrahydrofuran-2-yl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid (5R,6S)-6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(2R)-2-oxolanyl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid 6α-[(R)-1-hydroxyethyl]-2-[(R)-tetrahydrofuran-2-yl]pen-2-em-3-carboxylic acid Faropenem sodium hemipentahydrate USP/EP/BP (5R,6S)-6-((R)-1-Hydroxyethyl)-7-oxo-3-((R)-tetrahydrofuran-2-yl)-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid Faropenem-d5Q: What is Faropenem-d5 Q: What is the CAS Number of Faropenem-d5 Q: What are the applications of Faropenem-d5 Faropenem sodium hemi 5-hydrate Faropenem Sodium Impurity G 106560-14-9 22547-49-3 2C12H14NNaO5S5H20 2C12H14NO5S2Na5H2O API