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ChemicalBook >> CAS DataBase List >>OXOMEMAZINE

OXOMEMAZINE

CAS No.
3689-50-7
Chemical Name:
OXOMEMAZINE
Synonyms
Imakol;6847 RP;6487 RP;Dysedon;RP-6847;Doxergan;Dosegran;6847 R.P.;Oxomemazin;OXOEMAZINE
CBNumber:
CB1236273
Molecular Formula:
C18H22N2O2S
Molecular Weight:
330.44
MDL Number:
MFCD00868197
MOL File:
3689-50-7.mol
MSDS File:
SDS
Last updated:2024-11-19 23:02:33

OXOMEMAZINE Properties

Melting point 115°
Boiling point 492.4±34.0 °C(Predicted)
Density 1.1453 (rough estimate)
refractive index 1.6000 (estimate)
storage temp. Store at -20°C
solubility ≥ 33mg/mL in DMSO
form Solid
pka 9.31±0.28(Predicted)
color White to off-white
FDA UNII 305MB38V1C
ATC code R06AD08

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS06
Signal word  Danger
Hazard statements  H330-H311-H301
Precautionary statements  P260-P271-P284-P304+P340-P310-P320-P403+P233-P405-P501-P264-P270-P301+P310-P321-P330-P405-P501-P280-P302+P352-P312-P322-P361-P363-P405-P501
Toxicity LD50 oral in mouse: 140mg/kg

OXOMEMAZINE price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC O860005 (±)-Oxomemazine 3689-50-7 1g $920 2021-12-16 Buy
American Custom Chemicals Corporation API0009875 OXOMEMAZINE 95.00% 3689-50-7 1G $892.5 2021-12-16 Buy
ChemScene CS-0131898 Oxomemazine 3689-50-7 10mg $60 2021-12-16 Buy
American Custom Chemicals Corporation API0009875 OXOMEMAZINE 95.00% 3689-50-7 5MG $502.11 2021-12-16 Buy
Crysdot CD11134460 Oxomemazine 97% 3689-50-7 1g $680 2021-12-16 Buy
Product number Packaging Price Buy
O860005 1g $920 Buy
API0009875 1G $892.5 Buy
CS-0131898 10mg $60 Buy
API0009875 5MG $502.11 Buy
CD11134460 1g $680 Buy

OXOMEMAZINE Chemical Properties,Uses,Production

Originator

Doxergan,Specia,France,1964

Uses

(±)-Oxomemazine, is a phenothiazine-type antihistamines, that has also shown antibacterial activity against Mycobacterium tuberculosis.

Definition

ChEBI: Oxomemazine is a member of phenothiazines.

Manufacturing Process

Phenothiazine is reacted with 3-dimethylamino-2-methylpropyl chloride in the presence of sodium amide to give 3-(10-phenthiazinyl)-2-methyl-1dimethylaminopropane. 11.9 g of of this intermediate is dissolved with agitation in glacial acetic acid (120 cc). Pure sulfuric acid (d = 1.83; 0.5 cc) is added and a mixture of glacial acetic acid (10 cc) and hydrogen peroxide (8.5 cc of a solution containing 38 g of hydrogen peroxide in 100 cc) is then run in over 20 minutes. The temperature rises from 25°C to 35°C and is then kept at 60°C for 18 hours. The mixture is cooled and water (150 cc) is added and, with cooling, aqueous sodium hydroxide (d = 1.33; 220 cc). The resulting mixture is extracted with ethyl acetate (3 x 100 cc), the solvent is evaporated on a water bath and the residue is recrystallized from heptane (150 cc). 3(9,9-dioxy-10-phenthiazinyl)-2-methyl-1-dimethylaminopropane (78 g) is obtained, MP 115°C.
The corresponding hydrochloride prepared in ethyl acetate and recrystallized from a mixture of ethanol and isopropanol melts at 250°C.

Therapeutic Function

Antihistaminic

OXOMEMAZINE Preparation Products And Raw materials

OXOMEMAZINE Suppliers

Global( 55)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32161 58
Shijiazhuang Gantuo Biotechnology Co., Ltd 		+8613373514458 gantuo02@cngantuo.com China 203 58
AFINE CHEMICALS LIMITED 		+86-0571-85134551 sales@afinechem.com China 15352 58
Dayang Chem (Hangzhou) Co.,Ltd. 		571-88938639 +8617705817739 info@dycnchem.com China 52849 58
Shaanxi Didu New Materials Co. Ltd 		+86-89586680 +86-13289823923 1026@dideu.com China 8670 58
TargetMol Chemicals Inc. 		support@targetmol.com United States 38631 58
GIHI CHEMICALS CO.,LIMITED 		+8618058761490 info@gihichemicals.com China 49978 58
Hebei Miaoyin Technology Co.,Ltd 		+86-17367732028 +86-17367732028 kathy@hbyinsheng.com China 3512 58
LEAPCHEM CO., LTD. 		+86-852-30606658 market18@leapchem.com China 43340 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 52924 58

View Lastest Price from OXOMEMAZINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
OXOMEMAZINE pictures 2024-11-19 OXOMEMAZINE
3689-50-7
 US $0.00-30.00 / mg 99.49% 10g TargetMol Chemicals Inc.
Oxomemazine pictures 2023-06-26 Oxomemazine
3689-50-7
 US $200.00 / kg 1kg 99% 1000kg/Month Hebei Mingeng Biotechnology Co., Ltd
Oxomemazine pictures 2023-04-11 Oxomemazine
3689-50-7
 US $100.00 / g 10g 99% 1000g Shijiazhuang Gantuo Biotechnology Co., Ltd
  • OXOMEMAZINE pictures
  • OXOMEMAZINE
    3689-50-7
  • US $0.00-30.00 / mg
  • 99.49%
  • TargetMol Chemicals Inc.
  • Oxomemazine pictures
  • Oxomemazine
    3689-50-7
  • US $200.00 / kg
  • 99%
  • Hebei Mingeng Biotechnology Co., Ltd
  • Oxomemazine pictures
  • Oxomemazine
    3689-50-7
  • US $100.00 / g
  • 99%
  • Shijiazhuang Gantuo Biotechnology Co., Ltd

OXOMEMAZINE Spectrum

OXOMEMAZINE 10-(3-(Dimethylamino)-2-methylpropyl)phenothiazine-5,5-dioxide 10H-Phenothiazine-10-propanamine, N,N,beta-trimethyl-, 5,5-dioxide 3-(5,5-Dioxido-10H-phenothiazin-10-yl)-N,N,2-trimethyl-1-propanamine 6487 RP 6847 R.P. 6847 RP Alimemazine S,S-dioxide Dosegran Doxergan Dysedon Imakol Oxomemazin Oxymemazine Phenothiazine, 10-[3-(dimethylamino)-2-methylpropyl]-, 5,5-dioxide RP-6847 S,S-Dioxo-9,9-(dimethylamino-3-methyl-2-propyl)-10-phenothiazine Trimeprazine 5,5-dioxide Oxomemazinebase Oxomenazine OXOEMAZINE 10-(3-Dimethylamino-2-methylpropyl)-10H-phenothiazine 5,5-dioxide 10-[2-(Dimethylaminomethyl)propyl]-10H-phenothiazine 5,5-dioxide N,N,β-Trimethyl-10H-phenothiazine-10-propan-1-amine 5,5-dioxide [3-(5,5-diketophenothiazin-10-yl)-2-methyl-propyl]-dimethyl-amine 3-(5,5-dioxophenothiazin-10-yl)-N,N,2-trimethyl-propan-1-amine 3-(5,5-dioxophenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine 10H-Phenothiazine-10-propanamine, N,N,β-trimethyl-, 5,5-dioxide OxomemazineQ: What is Oxomemazine Q: What is the CAS Number of Oxomemazine Q: What is the storage condition of Oxomemazine Q: What are the applications of Oxomemazine histamine H1-receptor,OXOMEMAZINE,Histamine Receptor,inhibit,phenothiazine,antimuscarinic,muscarinic M1,Inhibitor,Metabotropic glutamate receptors,cough,anticholinergic,antihistamine,mGluR 3689-50-7