2-Iodobenzoic acid
- CAS No.
- 88-67-5
- Chemical Name:
- 2-Iodobenzoic acid
- Synonyms
- O-IODOBENZOIC ACID;2-IODO BENZONIC ACID;NSC 3772;usafek-572;USAF ek-572;'LGC' (4009);O-iodine acid;IodobenzoicAcid;2-lodhenxoieacid;2-iodo-benzoicaci
- CBNumber:
- CB1126640
- Molecular Formula:
- C7H5IO2
- Molecular Weight:
- 248.02
- MDL Number:
- MFCD00002419
- MOL File:
- 88-67-5.mol
- MSDS File:
- SDS
| Melting point | 160-162 °C(lit.) |
|---|---|
| Boiling point | 313.9±25.0 °C(Predicted) |
| Density | 2.25 |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | Soluble in dimethyl sulfoxide and methanol |
| pka | 2.85(at 25℃) |
| form | Powder, Crystals or Flakes |
| color | Light yellow to orange-brown |
| Water Solubility | sparingly soluble |
| Sensitive | Light Sensitive |
| Merck | 14,5030 |
| BRN | 1861406 |
| Stability | Stable. Incompatible with strong oxidizing agents, strong bases. |
| InChIKey | CJNZAXGUTKBIHP-UHFFFAOYSA-N |
| CAS DataBase Reference | 88-67-5(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 7Q00V80J7Q |
| NIST Chemistry Reference | Benzoic acid, 2-iodo-(88-67-5) |
| EPA Substance Registry System | Benzoic acid, 2-iodo- (88-67-5) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H315-H318-H335 | |||||||||
| Precautionary statements | P261-P264-P280-P301+P312-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 22-37/38-41-36/37/38-20/21/22 | |||||||||
| Safety Statements | 26-39-24/25-22-36 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | DH2975000 | |||||||||
| Hazard Note | Irritant | |||||||||
| TSCA | T | |||||||||
| HazardClass | IRRITANT, LIGHT SENSITIVE | |||||||||
| HS Code | 29163900 | |||||||||
| NFPA 704 |
|
2-Iodobenzoic acid price More Price(38)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | I7675 | 2-Iodobenzoic acid 98% | 88-67-5 | 25g | $28.4 | 2024-03-01 | Buy |
| Sigma-Aldrich | 418463 | 2-Iodobenzoic acid ≥99%, purified by sublimation | 88-67-5 | 1G | $34.6 | 2023-01-07 | Buy |
| TCI Chemical | I0053 | 2-Iodobenzoic Acid >98.0%(GC)(T) | 88-67-5 | 25g | $26 | 2024-03-01 | Buy |
| TCI Chemical | I0053 | 2-Iodobenzoic Acid >98.0%(GC)(T) | 88-67-5 | 100g | $73 | 2024-03-01 | Buy |
| Alfa Aesar | A10563 | 2-Iodobenzoic acid, 98+% | 88-67-5 | 25g | $23.65 | 2024-03-01 | Buy |
2-Iodobenzoic acid Chemical Properties,Uses,Production
Description
2-iodobenzoic acid and its derivatives are important pharmaceutical and chemical raw materials, which are necessary for the synthesis of various high-iodine reagents. It is commonly used as a precursor for the synthesis of 2-Iodoxybenzoic acid (IBX) and Dess-Martin peridinane, which are used as mild oxidants. It is also used in Suziki reaction.
Chemical Properties
white crystal powder. Soluble in alcohol and ether, insoluble in water.
Uses
Reagent for detection of sulfhydryl groups in proteins. 2-Iodobenzoic acid acts as a precursor in the preparation of 2-Iodoxybenzoic acid (IBX) and Dess-Martin periodinane, which finds application as an oxidizing agent in synthetic chemistry. It is also used in Suzuki reaction.
Preparation
2-Iodobenzoic acid is obtained from Anthranilic acid by diazotization and substitution. Diazotization of Anthranilic acid with sodium nitrite in the presence of sulfuric acid, control the temperature below 10℃, filter the diazotization solution, add the mixture of potassium iodide and sulfuric acid, stir for 10min after addition, and boil. Filter, wash with sodium thiosulfate solution, 2-Iodobenzoic acid can be recrystallized from water.
Application
2-Iodobenzoic acid can be used as a reactant in the synthesis of oligo(m-phenylene ethynylenes), (±)-lycoricidine and various detoxifiers of organophosphorus nerve agents. Additionally, it is used as a precursor in the preparation of oxidizing reagents like 2-iodoxybenzoic acid (IBX) and Dess-Martin periodinane (DMP).
Definition
ChEBI: An iodobenzoic acid with a single iodo substituent placed at the 2-position.
Synthesis Reference(s)
Journal of the American Chemical Society, 93, p. 4841, 1971 DOI: 10.1021/ja00748a029
Purification Methods
Crystallise the acid repeatedly from water and EtOH. Sublime it under vacuum at 100o. [Beilstein 9 IV 1030.]
2-Iodobenzoic acid Preparation Products And Raw materials
Raw materials
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Preparation Products
1of3
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Dalian Richfortune Chemicals Co., Ltd | 0411-84820922 8613904096939 | sales@richfortunechem.com | China | 304 | 57 |
| Mascot I.E.Co .,Ltd. | +86-0519-85010339 +8613584504415 | info@mascotchem.com | China | 327 | 58 |
| Hebei Weibang Biotechnology Co., Ltd | +8615531157085 | abby@weibangbio.com | China | 8810 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12835 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 5857 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5889 | 58 |
| Hebei Kingfiner Technology Development Co.Ltd | +86-15532196582 +86-15373005021 | lisa@kingfinertech.com | China | 3010 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 | Mandy@hangyubiotech.com | China | 10986 | 58 |
| Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 | qinhe02@xaltbio.com | China | 997 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20284 | 58 |
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View Lastest Price from 2-Iodobenzoic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-12-20 | 2-Iodobenzoic acid
88-67-5
|
US $100.00 / kg | 1kg | 99 | 5000 | Hebei Zhuanglai Chemical Trading Co.,Ltd | |
 |
2024-12-13 | 2-Iodobenzoic acid
88-67-5
|
US $0.00 / KG | 1KG | 98%min | 30tons/month | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2024-12-10 | 2-Iodobenzoic acid
88-67-5
|
US $0.00-0.00 / KG | 1KG | 99% | 20 mt | Hebei Weibang Biotechnology Co., Ltd |
-
- 2-Iodobenzoic acid
88-67-5
- US $100.00 / kg
- 99
- Hebei Zhuanglai Chemical Trading Co.,Ltd
-
- 2-Iodobenzoic acid
88-67-5
- US $0.00 / KG
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- 2-Iodobenzoic acid
88-67-5
- US $0.00-0.00 / KG
- 99%
- Hebei Weibang Biotechnology Co., Ltd