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ChemicalBook >> CAS DataBase List >>1-Methyl-3-nitro-1-nitrosoguanidine

1-Methyl-3-nitro-1-nitrosoguanidine

CAS No.
70-25-7
Chemical Name:
1-Methyl-3-nitro-1-nitrosoguanidine
Synonyms
MNNG;MNG;Methylnitronitrosoguanidine;1-methyl-3-nitro-1-nitroso-guanidin;N-METHYL-N'-NITRO-N-NITROSOGUANIDINE;NA 1325;nsc9369;NSC 9369;nci-c01423;rcrawastenumberu163
CBNumber:
CB0730037
Molecular Formula:
C2H5N5O3
Molecular Weight:
147.09
MDL Number:
MFCD00007034
MOL File:
70-25-7.mol
MSDS File:
SDS
Last updated:2024-12-18 13:37:16

1-Methyl-3-nitro-1-nitrosoguanidine Properties

Melting point 118°C (dec.)
Boiling point 267.16°C (rough estimate)
Density 1.7979 (rough estimate)
refractive index 1.6410 (estimate)
storage temp. 0-6°C
solubility almost transparency in hot Methanol
form powder to crystal
pka 3.09±0.50(Predicted)
color Light yellow to Brown
Water Solubility Reacts violently
Merck 14,6103
Stability Unstable. Reacts violently with water. May detonate under impact. Heat, light and moisture sensitive. May explode if stored in sealed ampules. Highly flammable. Incompatible with aqueous solutions, acids, bases, oxidizing agents, reducing agents. Alkaline hydrolysis releases toxic and explosive gases.
InChIKey VZUNGTLZRAYYDE-UHFFFAOYSA-N
CAS DataBase Reference 70-25-7(CAS DataBase Reference)
EWG's Food Scores 2
FDA UNII 12H3O2UGSF
Proposition 65 List N-Methyl-N'-nitro-N-nitrosoguanidine
IARC 2A (Vol. 4, Sup 7) 1987
NIST Chemistry Reference Guanidine, n-methyl-n'-nitro-n-nitroso-(70-25-7)
EPA Substance Registry System

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS02,GHS06,GHS07,GHS08,GHS09
Signal word  Danger
Hazard statements  H228-H301-H315-H319-H332-H350-H411
Precautionary statements  P201-P202-P210-P240-P241-P261-P264-P270-P271-P273-P280-P301+P310+P330-P302+P352+P332+P313+P362+P364-P304+P340+P312-P305+P351+P338+P337+P313-P308+P313-P391-P405-P501
Hazard Codes  T;N,N,T
Risk Statements  45-20-36/38-51/53
Safety Statements  53-45-61
RIDADR  2926
RTECS  MF4200000
HS Code  2925.29.9000
HazardClass  4.1
PackingGroup  II
Hazardous Substances Data 70-25-7(Hazardous Substances Data)
Toxicity LD50 oral in rat: 90mg/kg
NFPA 704
2
2 0

1-Methyl-3-nitro-1-nitrosoguanidine price More Price(7)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical M0527 1-Methyl-3-nitro-1-nitrosoguanidine (wetted with ca. 50% Water) (unit weight on dry weight basis) >95.0%(T) 70-25-7 5g $89 2021-12-16 Buy
TCI Chemical M0527 1-Methyl-3-nitro-1-nitrosoguanidine (wetted with ca. 50% Water) (unit weight on dry weight basis) >95.0%(T) 70-25-7 25g $313 2021-12-16 Buy
TRC N493990 N’-Nitro-N-nitroso-N-methylguanidine(StabilizedwithWater) 70-25-7 100mg $45 2021-12-16 Buy
American Custom Chemicals Corporation NUC0003097 N-METHYL-N'-NITRO-N-NITROSOGUANIDINE 95.00% 70-25-7 100MG $721.88 2021-12-16 Buy
Matrix Scientific 168011 1-Methyl-3-nitro-1-nitrosoguanidine 70-25-7 25g $792 2021-12-16 Buy
Product number Packaging Price Buy
M0527 5g $89 Buy
M0527 25g $313 Buy
N493990 100mg $45 Buy
NUC0003097 100MG $721.88 Buy
168011 25g $792 Buy

1-Methyl-3-nitro-1-nitrosoguanidine Chemical Properties,Uses,Production

Chemical Properties

yellow to pink crystals

Uses

Experimentally as carcinogen and mutagen. Formerly in preparation of diazomethane.

Uses

A DNA-damaging agent, used as a positive control in SHE cell transformation assays.

Production Methods

MNNG is one of the first chemical mutagens and is a stabilized form of methylnitrosoguanidine, which has not been isolated. It does not occur in nature, and human exposure to it is limited to laboratories.

Definition

ChEBI: An N-nitroguanidine compound having nitroso and methyl substituents at the N'-position

General Description

A yellow powder. Melting point 244°F. Decomposes above 212°F. A suspected carcinogen. Extremely hazardous as a mutagen. Avoid skin contact and inhalation of of vapors. Usually stored frozen (below 32°F) in polyethylene bottles that are tightly closed and contained in a metal can. May decomposed during prolonged storage and develop sufficient pressure in a closed container to explode. Keep away from heat, sparks, and open flame.

Air & Water Reactions

Highly flammable. Reacts violently with water .

Reactivity Profile

1-Methyl-3-nitro-1-nitrosoguanidine will detonate under high impact. 1-Methyl-3-nitro-1-nitrosoguanidine is sensitive to heat. A sample has exploded when melted in a sealed capillary tube. Incompatible with acids, bases, oxidizing agents and reducing agents. Reacts with bases to release highly toxic, irritating and explosive gases. Reacts slowly with acids to release nitrous acid. Reacts with various nucleophiles, especially amines and thiols. Reacts with aqueous potassium hydroxide to form a highly reactive compound. The crude product from aqueous nitrosation is pyrophoric but recrystallized material is stable .

Health Hazard

Fire may produce irritating and/or toxic gases. Contact may cause burns to skin and eyes. Contact with molten substance may cause severe burns to skin and eyes. Runoff from fire control may cause pollution.

Fire Hazard

Flammable/combustible material. May be ignited by friction, heat, sparks or flames. Some may burn rapidly with flare burning effect. Powders, dusts, shavings, borings, turnings or cuttings may explode or burn with explosive violence. Substance may be transported in a molten form at a temperature that may be above its flash point. May re-ignite after fire is extinguished.

Safety Profile

Confirmed carcinogen with experimental carcinogenic, tumorigenic, and teratogenic data. Poison by ingestion, intraperitoneal, and intravenous routes. Moderately toxic by subcutaneous route. Experimental reproductive effects. Human mutation data reported. An explosive sensitive to heat or impact. Flammable when exposed to heat or flame; can react vigorously with oxidizing materials. When heated to decomposition it emits very toxic fumes of NOx.

Carcinogenicity

N-Methyl-N-nitro-N-nitrosoguanidine (MNNG) is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.

4245-76-5
70-25-7
Synthesis of 1-Methyl-3-nitro-1-nitrosoguanidine from 1-Methyl-3-nitroguanidine

1-Methyl-3-nitro-1-nitrosoguanidine Preparation Products And Raw materials

Global( 171)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29791 60
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21634 55
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29880 58
Chongqing Chemdad Co., Ltd 		+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39894 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49374 58
Zhengzhou Alfa Chemical Co.,Ltd 		+8618530059196 sale04@alfachem.cn China 11818 58
Hubei Ipure Biology Co., Ltd 		+8613367258412 ada@ipurechemical.com China 10319 58
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58
HONG KONG IPURE BIOLOGY CO.,LIMITED 		86 18062405514 18062405514 ada@ipurechemical.com CHINA 3461 58
Wuhan Monad Medicine Tech Co.,LTD 		02768782018 18771942761 sales01@whmonad.com CHINA 979 58

View Lastest Price from 1-Methyl-3-nitro-1-nitrosoguanidine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-Methyl-3-nitro-1-nitrosoguanidine pictures 2021-08-31 1-Methyl-3-nitro-1-nitrosoguanidine
70-25-7
 US $10.00 / KG 1KG 99.99% 20 tons/month Wuhan Monad Medicine Tech Co.,LTD
1-Methyl-3-nitro-1-nitrosoguanidine pictures 2021-08-12 1-Methyl-3-nitro-1-nitrosoguanidine
70-25-7
 US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
1-Methyl-3-nitro-1-nitrosoguanidine pictures 2019-07-06 1-Methyl-3-nitro-1-nitrosoguanidine
70-25-7
 US $1.00 / KG 1KG 98% 1kg,5kg,100kg Career Henan Chemical Co
1-nitroso-3-nitro-1-methylguanidine Guanidine, 1-methyl-3-nitro-1-nitroso- mnng(n-methyl-n’-nitro-n-nitrosoguanidine n’-nitro-n-nitroso-n-methylguanidine NA 1325 nci-c01423 N-Methyl-N',2-dioxohydrazinecarboximidohydrazide 2-oxide n-methyl-n’-nitro-n-nitroso-guanidin N-Methyl-N-nitrosonitroguanidin n-methylo-n’-nitro-n-nitrozoguanidyny(polish) N-Methyl-N'-nitro-N-nitrosoguanidine (wetted with ca. 50% Water, containing 5g on a dry weight basis) Guanidine, N-methyl-N-nitro-N-nitroso- NMETHYLNNITRONITROSOGUANIDINE 1-METHYL-3-NITRO-NITROSOGUANIDINE METHYL-N-NITRO-N-NITROSOGUANIDINE NITROSOMETHYLNITROGUANIDINE METHYLNITROSONITROGUANIDINE NITROSO-NITRO-METHYLGUANIDINE N-METHYL-N''-NITRO-N-NITROSOGUANIDINE , WETTED WITH 50% WATER Diazomethane precursor, MNNG, N-Methyl-Nμ-nitro-N-nitrosoguanidine 1-Methyl-2-nitro-1-nitrosoguanidine 3-Methyl-1-nitro-3-nitrosoguanidine 1-Methyl-3-nitro-1-nitrosoguanidine (wetted with ca. 50% Water) (unit weight on dry weight basis) 1-METHYL-3-NITRO-1-NITROSOGUANIDINE 1-Methyl-3-nitro-1-nitrosoguanidine (wetted with ca. 50% Water, containing 5g on a dry weight basis) N-METHYL-n,n'-NITROSOGUANIDINE N-Methyl-N'-nitro-N-nitrosoguanidine ,97% N-METHYL-N'-NITRO-N-NITROSOGUANIDINE, MO ISTENED WITH WATER (wetted with ca. 50% Water, containing 5g on a dry weight basis) 1-Methyl-3-nitro-1-nitrosoguanidine  1-Methyl-1-Nitroso-3-nitroguanidine n-metylo-n’-nitro-n-nitrozoguanidyny n-metylo-n’-nitro-n-nitrozoguanidyny(polish) N-Metylo-N'-nitro-N-nitrozoguanidyny N'-Nitro-N-nitroso-N-methylguanidine n-nitroso-n’-nitro-n-methylguanidine N-Nitroso-N-methylnitroguanidine NSC 9369 nsc9369 Rcra waste number U163 rcrawastenumberu163 DIAZOMETHANE PRECURSOR N-METHYL-N-NITROSO-N'-NITROGUANIDINE 1-METHYL-3-NITRO-1-NITROSOGUANIDINE, MOISTENED WITH WATER 1-Methyl-3-nitro-1-nitrosoguanidine (wetted with ca. 50% Water) N-Methyl-N′-nitro-N-nitrosoguanidine (wetted with ca. 50% water) N-Methyl-N'-nitro-N-nitrosoguanidine@100 μg/mL in Toluene 1-Methyl-3-nitro-1-nitrosoguanidine(wettedwithca.50%Water,containing5gonadryweightbasis)> N’-Nitro-N-nitroso-N-methylguanidine (Stabilized with Water) 1-METHYL-3-NITRO-1-NITROSOGUANIDINE (~50% WATER W/W. UNIT WEIGHT ON DRY BASIS) 1-Methyl-3-nitro-1-nitrosouanidine N’-Nitro-N-nitroso-N-methylguanidine (Stabilized with Water) (1.0 mg/mL in Methanol) 1-methyl-3-nitro-1-nitroso-guanidin Methylnitronitrosoguanidine MNG MNNG N-METHYL-N'-NITRO-N-NITROSOGUANIDINE N’-Nitro-N-nitroso-N-methylguanidine (Stabilized with 40% Water)