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ChemicalBook >> CAS DataBase List >>1H-Benz[de]isoquinolin-1-one,2,4,5,6-tetrahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]-

1H-Benz[de]isoquinolin-1-one,2,4,5,6-tetrahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]-

CAS No.
1021456-82-5
Chemical Name:
1H-Benz[de]isoquinolin-1-one,2,4,5,6-tetrahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]-
Synonyms
Palonosetron USP RC B;Palonosetron Impurity 2;Palonosetron USP Impurity B;Dehydro N-Oxide Palonosetron;Dehydro palonosetron N-oxide;Palonosetron USP Related Compound B;Palonosetron USP Related Compound B HCl;Palonosetron Related Compound B (Palonosetron-3-ene N-Oxide);Palonosetron Impurity 13 (Palonosetron USP Related Compound B);(S)-3-(1-oxo-5,6-dihydro-1H-benzo[de]isoquinolin-2(4H)-yl)quinuclidine1-oxide
CBNumber:
CB03133165
Molecular Formula:
C19H22N2O2
Molecular Weight:
310.39
MDL Number:
MFCD32671828
MOL File:
1021456-82-5.mol
Last updated:2023-05-15 10:43:34

1H-Benz[de]isoquinolin-1-one,2,4,5,6-tetrahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]- Properties

solubility Methanol (Slightly), Water (Slightly)
form Solid
pka 4.72±0.40(Predicted)
color Off-White to Pale Yellow
FDA UNII FZY2QC85ZS

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330-P501
HS Code  2933790002

1H-Benz[de]isoquinolin-1-one,2,4,5,6-tetrahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC P165820 Palonosetron-3-eneN-Oxide 1021456-82-5 10mg $215 2021-12-16 Buy
Medical Isotopes, Inc. 85079 Palonosetron-3-eneN-oxide 1021456-82-5 10mg $390 2021-12-16 Buy
Product number Packaging Price Buy
P165820 10mg $215 Buy
85079 10mg $390 Buy

1H-Benz[de]isoquinolin-1-one,2,4,5,6-tetrahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]- Chemical Properties,Uses,Production

Uses

Palonosetron-3-ene N-Oxide is an impurity of Palonosetron (P165800), a serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Antiemetic.

1H-Benz[de]isoquinolin-1-one,2,4,5,6-tetrahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]- Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 54)Suppliers
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Standardpharm Co. Ltd. 		86-714-3992388 overseasales1@yongstandards.com United States 14332 58
Career Henan Chemica Co 		+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30241 58
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GIHI CHEMICALS CO.,LIMITED 		+8618058761490 info@gihichemicals.com China 49979 58
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Guangzhou PI PI Biotech Inc 020-81716320 +86-13602409664 Sales@pipitech.com China 3633 55
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 14055 65
Beijing Comparison Pharmaceutical Technology Co., Ltd 010-010-52878169 15801002657 sales@bjcomparison.com China 4949 58
ChemStrong Scientific Co.,Ltd 0755-0755-66853366 13670046396 sales@chem-strong.com China 18043 56
Palonosetron Impurity 2 Palonosetron Related Compound B ((3S)-3-(1-Oxo-5,6-dihydro-1H-benzo[de]isoquinolin-2(4H)-yl)quinucl (1492233) Dehydro N-Oxide Palonosetron (S)-3-(1-oxo-5,6-dihydro-1H-benzo[de]isoquinolin-2(4H)-yl)quinuclidine 1-oxide HCl Palonosetron Related Compound B (Palonosetron-3-ene N-Oxide) Dehydro palonosetron N-oxide Palonosetron USP Related Compound B HCl (S)-3-(1-oxo-5,6-dihydro-1H-benzo[de]isoquinolin-2(4H)-yl)quinuclidine1-oxide Palonosetron USP Related Compound B Palonosetron USP RC B 2-[(3S)-1-oxido-1-azoniabicyclo[2.2.2]octan-3-yl]-5,6-dihydro-4H-benzo[de]isoquinolin-1-one Palonosetron USP Impurity B Palonosetron Impurity 13 (Palonosetron USP Related Compound B) 1021456-82-5