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ChemicalBook >> CAS DataBase List >>POLYOXIN D

POLYOXIN D

CAS No.
22976-86-9
Chemical Name:
POLYOXIN D
Synonyms
polyoxinz;polyoxorim;POLYOXIN D;POLYOXIN D, STREPTOMYCES CACAOI VAR ASOENSIS;Polyoxin D,?Streptomyces cacaoi var. asoensis CURRENTLY UNAVAILABLE;2,3,4-tetrahydro-2,4-dioxo-d-allofuranuronosyl)-monocarbamate(ester);1-(5-(2-amino-2-deoxy-l-xylonamido)-5-deoxy-beta-5-pyrimidinecarboxylicaci;1-[5-[[2-Amino-5-O-(aminocarbonyl)-2-deoxy-L-xylonoyl]amino]-5-deoxy-β-D-allofuranulonosyl]-1,2,3,4-tetrahydro-2,4-dioxo-5-pyridinecarboxylic acid;1-[5-[[2-Amino-5-O-(aminocarbonyl)-2-deoxy-L-xylonoyl]amino]-5-deoxy-β-D-allofuranuronosyl]-1,2,3,4-tetrahydro-2,4-dioxo-5-pyrimidinecarboxylic acid;β-D-Allofuranuronic acid, 5-[[2-amino-5-O-(aminocarbonyl)-2-deoxy-L-xylonoyl]amino]-1-(5-carboxy-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-1,5-dideoxy-
CBNumber:
CB0265177
Molecular Formula:
C17H23N5O14
Molecular Weight:
521.39
MDL Number:
MFCD00166352
MOL File:
22976-86-9.mol
MSDS File:
SDS
Last updated:2025-01-21 14:14:50

POLYOXIN D Properties

Melting point 173-175 °C (decomp)
Density 1.864±0.06 g/cm3(Predicted)
storage temp. 10-30°C
pka 2.67±0.10(Predicted)
form solid
color white
Water Solubility aqueous buffer: soluble
water: soluble
FDA UNII A2468O1N7D

POLYOXIN D price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC P688083 PolyoxinD,?Streptomycescacaoivar.asoensisCURRENTLYUNAVAILABLE 22976-86-9 2.5mg $500 2021-12-16 Buy
TRC P688083 PolyoxinD,?Streptomycescacaoivar.asoensisCURRENTLYUNAVAILABLE 22976-86-9 10mg $1865 2021-12-16 Buy
Product number Packaging Price Buy
P688083 2.5mg $500 Buy
P688083 10mg $1865 Buy

POLYOXIN D Chemical Properties,Uses,Production

Uses

Polyoxin D,?Streptomyces cacaoi var. asoensis is a specific inhibitor of fungal chitin synthetase.

Definition

ChEBI: A member of the class of polyoxins that is isolated from the soil organism Streptomyces cacaoi var. asoensis. Polyoxorim exhibits fungicidal properties and may be used on rice, industrial grounds, golf courses and parks.

Enzyme inhibitor

This pyrimidin nucleoside analogue and antifungal antibiotic (FWfree-acid = 521.39 g/mol; CAS 22976-86-9; 33401-46-6 for the zinc salt), produced by soil organisms Streptomyces cacaoi and S. piomogenus, inhibits chitin biosynthesis, Ki = 6 μM, thereby blocking septum formation. The zinc salt of polyyoxin is used to control Rice Sheath Blight, caused by the fungus Rhizoctonia solani, as well as the turfgrass disease Brown Patch, caused by other Rhizoctonia species. Polyoxin D also inhibits Neurospora crassa, but is nontoxic to land mammals, insects, or birds, when applied to plants as the wettable powder form known as Endorse?. Target(s): chitin synthase (1- 24); chitin synthase B; chitin synthase, canChs1A; WdChs4p, a chitin synthase 3 homologue.

POLYOXIN D Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 27)Suppliers
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Hubei Jusheng Technology Co.,Ltd. 		18871490254 linda@hubeijusheng.com CHINA 28172 58
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Guangzhou Younan Technology Co., Ltd 020-82000279 18988968278 sales@ubiochem.com China 4297 58
2,3,4-tetrahydro-2,4-dioxo-d-allofuranuronosyl)-monocarbamate(ester) polyoxinz polyoxorim 1-[5-[[2-Amino-5-O-(aminocarbonyl)-2-deoxy-L-xylonoyl]amino]-5-deoxy-β-D-allofuranulonosyl]-1,2,3,4-tetrahydro-2,4-dioxo-5-pyridinecarboxylic acid 1-[5-[[2-Amino-5-O-(aminocarbonyl)-2-deoxy-L-xylonoyl]amino]-5-deoxy-β-D-allofuranuronosyl]-1,2,3,4-tetrahydro-2,4-dioxo-5-pyrimidinecarboxylic acid POLYOXIN D POLYOXIN D, STREPTOMYCES CACAOI VAR ASOENSIS 1-(5-(2-amino-2-deoxy-l-xylonamido)-5-deoxy-beta-5-pyrimidinecarboxylicaci β-D-Allofuranuronic acid, 5-[[2-amino-5-O-(aminocarbonyl)-2-deoxy-L-xylonoyl]amino]-1-(5-carboxy-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-1,5-dideoxy- Polyoxin D,?Streptomyces cacaoi var. asoensis CURRENTLY UNAVAILABLE 22976-86-9 C17H23N5O14