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ChemicalBook >> CAS DataBase List >>Fluphenazine decanoate

Fluphenazine decanoate

CAS No.
5002-47-1
Chemical Name:
Fluphenazine decanoate
Synonyms
lyogen;ecanoate;dapotumd;sq10,733;modecate;moditendepot;zinyl)ethylester;prolixindecanoate;fluphenazinedepot;flufenazinedecanoate
CBNumber:
CB0260394
Molecular Formula:
C32H44F3N3O2S
Molecular Weight:
591.77
MDL Number:
MFCD00798504
MOL File:
5002-47-1.mol
Last updated:2024-07-02 08:54:57

Fluphenazine decanoate Properties

Melting point 30-32°
Boiling point 658.1±55.0 °C(Predicted)
Density 1.149±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Practically insoluble in water, very soluble in ethanol and in methylene chloride, freely soluble in methanol.
form Oil
pka 7.32±0.10(Predicted)
color Light yellow to yellow
CAS DataBase Reference 5002-47-1
FDA UNII FMU62K1L3C

Pharmacokinetic data

Protein binding >90%
Excreted unchanged in urine 20%
Volume of distribution 10
Biological half-life 6-9 days / 14-26 days

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS06,GHS08
Signal word  Danger
Hazard statements  H300-H361
Precautionary statements  P201-P202-P264-P270-P280-P301+P310
RIDADR  3249
RTECS  HE0525000
HazardClass  6.1(a)
PackingGroup  II

Fluphenazine decanoate price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich F0260000 Fluphenazine decanoate European Pharmacopoeia (EP) Reference Standard 5002-47-1 f0260000 $153 2024-03-01 Buy
TRC F598300 FluphenazineDecanoate(~90%) 5002-47-1 500mg $965 2021-12-16 Buy
ChemScene CS-0013962 Fluphenazine decanoate 99.48% 5002-47-1 100mg $220 2021-12-16 Buy
American Custom Chemicals Corporation API0009087 FLUPHENAZINE DECANOATE 95.00% 5002-47-1 25MG $225.75 2021-12-16 Buy
AK Scientific J96004 Fluphenazine decanoate 5002-47-1 250mg $320 2021-12-16 Buy
Product number Packaging Price Buy
F0260000 f0260000 $153 Buy
F598300 500mg $965 Buy
CS-0013962 100mg $220 Buy
API0009087 25MG $225.75 Buy
J96004 250mg $320 Buy

Fluphenazine decanoate Chemical Properties,Uses,Production

Chemical Properties

Yellow Oil

Uses

Fluphenazine Decanoate is used in psychotropic drug treatments like those relating to schizophrenia. Antipsychotic.

Definition

ChEBI: Fluphenazine decanoate is the prodrug of fluphenazine, an antipsychotic drug used for the symptomatic management of psychosis in patients with schizophrenia. It has a role as a phenothiazine antipsychotic drug, a prodrug and a dopaminergic antagonist. It is a member of phenothiazines, a decanoate ester, an organofluorine compound and a N-alkylpiperazine. It is functionally related to a fluphenazine.

Clinical Use

Antipsychotic
Schizophrenia and other psychoses

Drug interactions

Potentially hazardous interactions with other drugs
Anaesthetics: enhanced hypotensive effect.
Analgesics: increased risk of convulsions with tramadol; enhanced hypotensive and sedative effects with opioids.
Anti-arrhythmics: increased risk of ventricular arrhythmias with anti-arrhythmics that prolong the QT interval; increased risk of ventricular arrhythmias with amiodarone and dronedarone - avoid; increased risk of ventricular arrhythmias with disopyramide.
Antibacterials: increased risk of ventricular arrhythmias with delamanid and moxifloxacin - avoid
Antidepressants: increased risk of ventricular arrhythmias with tricyclics, citalopram, escitalopram; possible increased risk of convulsions with vortioxetine
Antiepileptics: antagonises anticonvulsant effect.
Antimalarials: increased risk of ventricular arrhythmias with artenimol with piperaquine and artemether/lumefantrine - avoid.
Antipsychotics: increased risk of ventricular arrhythmias with droperidol, pimozide and risperidone - avoid; avoid use of depot formulations with clozapine (cannot be withdrawn quickly if neutropenia occurs).
Antivirals: increased risk of ventricular arrhythmias with saquinavir - avoid; concentration possibly increased with ritonavir.
Anxiolytics and hypnotics: increased sedative effects
Atomoxetine: increased risk of ventricular arrhythmias.
Beta-blockers: enhanced hypotensive effect; increased risk of ventricular arrhythmias with sotalol
Cytotoxics: increased risk of ventricular arrhythmias with arsenic trioxide
Diuretics: enhanced hypotensive effect.
Lithium: increased risk of extrapyramidal side effects and possibly neurotoxicity.
Pentamidine: increased risk of ventricular arrhythmias - avoid.
Avoid with drugs that prolong the QT interval.

Metabolism

The cytochrome P450 isoenzyme CYP2D6 is involved in fluphenazine metabolism.

Fluphenazine decanoate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 108)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21638 55
Chongqing Chemdad Co., Ltd
+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39894 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49374 58
Shaanxi Dideu Medichem Co. Ltd
+86-29-87569266 15319487004 1015@dideu.com China 4087 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34553 58
Xi'an MC Biotech, Co., Ltd.
029-89275612 +8618991951683 mcbio_sales@163.com China 2251 58
AFINE CHEMICALS LIMITED
+86-0571-85134551 sales@afinechem.com China 15356 58
CR Corporation Limited
+8613062833949 fred.wen@crcorporation.cn China 8647 58
Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207 sales@molcore.com China 49734 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38463 58

View Lastest Price from Fluphenazine decanoate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
 Fluphenazine decanoate  pictures 2022-09-30 Fluphenazine decanoate
5002-47-1
US $0.00-0.00 / KG 1KG 98% 1ton Henan Aochuang Chemical Co.,Ltd.
FluphenazineCecanoate FLUPHENAZINEDECANATE Decanoic acid, 2-[4-[3-[2-(trifluoromethyl) -10H-phenothiazin-10-yl]propyl]-1-piperazinyl]ethyl ester Decanoic acid 2-[4-[3-(2-trifluoromethyl-10H-phenothiazin-10-yl)propyl]piperazin-1-yl]ethyl ester Decanoic acid fluphenazine 2-(4-(3-(2-(trifluoromethyl)phenothiazin-10-yl)propyl)-1-piperazinyl)ethyld dapotumd decanoicacid,2-(4-(3-(2-(trifluoromethyl)phenothiazin-10-yl)propyl)-1-pipera ecanoate flufenazinedecanoate prolixindecanoate sq10,733 zinyl)ethylester 2-(4-(3-(2-(trifluoroMethyl)-10H-phenothiazin-10-yl)propyl)piperazin-1-yl)ethyl decanoate modecate moditendepot fluorophenazinedecanoate fluphenazinedepot lyogen FLUPHENAZINE DECANOATE fluphenazine o-decanoate 2-[4-[3-(2-(TRIFLUOROMETHYL)PHENOTHIAZIN-10-YL)PROPYL]PIPERAZIN-1-YL]ETHYL DECANOATE Fluphenazine Decanoate (~90%) Fluphenazine octanoate CRS Fluphenazine decanoate CRS butanoic acid 2-[4-[3-[2-(trifluoromethyl)-10-phenothiazinyl]propyl]-1-piperazinyl]ethyl ester 5002-47-1 C32H44F3N3O2S 59177 Organics API