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ChemicalBook >> CAS DataBase List >>N''-[N-METHOXYCARBONYL-L-VALYL]-N-[(S)-3,3,3-TRIFLUOR-1-ISOPROPYL-2-OXOPROPYL]-L-PROLINAMIDE

N''-[N-METHOXYCARBONYL-L-VALYL]-N-[(S)-3,3,3-TRIFLUOR-1-ISOPROPYL-2-OXOPROPYL]-L-PROLINAMIDE

CAS No.
182073-77-4
Chemical Name:
N''-[N-METHOXYCARBONYL-L-VALYL]-N-[(S)-3,3,3-TRIFLUOR-1-ISOPROPYL-2-OXOPROPYL]-L-PROLINAMIDE
Synonyms
ZD8321;ZD-8321,ZD8321;N''-[N-METHOXYCARBONYL-L-VALYL]-N-[(S)-3,3,3-TRIFLUOR-1-ISOPROPYL-2-OXOPROPYL]-L-PROLINAMIDE;L-Prolinamide, N-(methoxycarbonyl)-L-valyl-N-[(1S)-3,3,3-trifluoro-1-(1-methylethyl)-2-oxopropyl]-
CBNumber:
CB01476918
Molecular Formula:
C18H28F3N3O5
Molecular Weight:
423.43
MDL Number:
MFCD00949903
MOL File:
182073-77-4.mol
Last updated:2024-10-28 23:16:16

N''-[N-METHOXYCARBONYL-L-VALYL]-N-[(S)-3,3,3-TRIFLUOR-1-ISOPROPYL-2-OXOPROPYL]-L-PROLINAMIDE Properties

Boiling point 573.9±50.0 °C(Predicted)
Density 1.232±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
form Solid
pka 11.22±0.46(Predicted)
color Light yellow to yellow
FDA UNII T7FIA2S66D

N''-[N-METHOXYCARBONYL-L-VALYL]-N-[(S)-3,3,3-TRIFLUOR-1-ISOPROPYL-2-OXOPROPYL]-L-PROLINAMIDE price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
American Custom Chemicals Corporation KIN0001252 ZD-8321 95.00% 182073-77-4 5MG $503.07 2021-12-16 Buy
Product number Packaging Price Buy
KIN0001252 5MG $503.07 Buy

N''-[N-METHOXYCARBONYL-L-VALYL]-N-[(S)-3,3,3-TRIFLUOR-1-ISOPROPYL-2-OXOPROPYL]-L-PROLINAMIDE Chemical Properties,Uses,Production

Biological Activity

ZD8321 is a potent inhibitor of human Neutrophil elastase (NE) with a Ki value of 13±1.7 nM.

in vitro

TNFα-activated HUVEC is dose dependently inhibited by ZD8321.The adhesion between cancer cells with high elastase activity and TNFα-activated HUVEC is also inhibited by ZD8321.

target

Ki: 13±1.7 nM (Neutrophil elastase)

N''-[N-METHOXYCARBONYL-L-VALYL]-N-[(S)-3,3,3-TRIFLUOR-1-ISOPROPYL-2-OXOPROPYL]-L-PROLINAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

N''-[N-METHOXYCARBONYL-L-VALYL]-N-[(S)-3,3,3-TRIFLUOR-1-ISOPROPYL-2-OXOPROPYL]-L-PROLINAMIDE Suppliers

Global( 9)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32002 58
TargetMol Chemicals Inc. 		+8613564774135 zijue.cai@tsbiochem.com United States 19863 58
MedChemexpress LLC 021-58955995 sales@medchemexpress.cn United States 4861 58
Sichuan Wei Keqi Biological Technology Co., Ltd. 028-81700200 18116577057 3003855609@qq.com China 7887 56
BOC Sciences -- info@bocsci.com USA 0 65
Jinan ponder chemical co. LTD 0531-0000 thinklifescience@163.com China 19689 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 15801484223; psaitong@jm-bio.com China 29774 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24649 58

View Lastest Price from N''-[N-METHOXYCARBONYL-L-VALYL]-N-[(S)-3,3,3-TRIFLUOR-1-ISOPROPYL-2-OXOPROPYL]-L-PROLINAMIDE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
ZD8321 pictures 2024-10-28 ZD8321
182073-77-4
 US $1520.00-2500.00 / mg 10g TargetMol Chemicals Inc.
  • ZD8321 pictures
  • ZD8321
    182073-77-4
  • US $1520.00-2500.00 / mg
  • TargetMol Chemicals Inc.
N''-[N-METHOXYCARBONYL-L-VALYL]-N-[(S)-3,3,3-TRIFLUOR-1-ISOPROPYL-2-OXOPROPYL]-L-PROLINAMIDE ZD8321 L-Prolinamide, N-(methoxycarbonyl)-L-valyl-N-[(1S)-3,3,3-trifluoro-1-(1-methylethyl)-2-oxopropyl]- ZD-8321,ZD8321 182073-77-4 C18H28F3N3O5