雙醋炔諾醇 MSDS

19-Nor-17a-pregn-4-en-20-yne-3b,17-diol diacetate

雙醋炔諾醇性質、用途與生產工藝

生物活性

Ethynodiol diacetate (8080 CB) 是第一批合成的避孕藥用孕激素之一。

靶點

Target	Value
Progesterone receptor

體外研究

去甲二氫愈創(chuàng)木酸(NDGA) (< 1.5 μM)在150 μg/mL ethynodiol diacetate處理的人淋巴細胞中可以降低姐妹染色單體的交換率(SCEs)。在S9混合物存在的情況下NDGA處理會減輕ethynodiol diacetate 引起的遺傳毒性損傷，這可能是通過對細胞色素P450s的抑制實現的而P450s會阻止ethynodiol diacetate的代謝活化，也可能是由于 NDGA具有清除自由基的功能。在S9混合物存在的情況下， Ethynodiol diacetate (150 μg/mL)會增加人淋巴細胞中姐妹染色單體的交換率(SCEs)和染色體畸變(CAs)頻率并能 抑制淋巴細胞增殖。

體內研究

每天6 mg/kg劑量 Ethynodiol diacetate 可以顯著增加雌性大鼠尿液中3alpha-hydroxy-5alpha-pregnan-20-one 和A-homo-3-oxa-5alpha-pregnane-4,20-dione的含量，也可以顯著增加大鼠腦垂體，肝臟和腎臟的重量 。Norgestrel (75 μg/天)和ethynodiol diacetate (150 μg/天)以及ethinyl estradiol (7.5 μg/天)聯用可以降低食蟹猴高密度脂蛋白膽固醇的血漿濃度

雙醋炔諾醇 上下游產品信息

上游原料

下游產品

雙醋炔諾醇 試劑級價格

更新日期	產品編號	產品名稱	CAS編號	包裝	價格
2024/11/08	HY-B1089	雙醋炔諾醇 Ethynodiol diacetate	297-76-7	500mg	600元
2024/11/08	HY-B1089	雙醋炔諾醇 Ethynodiol diacetate	297-76-7	10mM * 1mLin DMSO	660元

雙醋炔諾醇 生產廠家

 

297-76-7, 雙醋炔諾醇 相關搜索:

• VUMIDE
• 抑制劑
• 化學試劑
• 藥靶配體
• 代謝物
• 原料藥
• 醫(yī)用中間體
• 醫(yī)藥原料
• 醫(yī)藥中間體
• 其它含氧化合物
• 內分泌與激素
• 小分子抑制劑
• 酸炔諾醇
• 雙醋炔若醇
• (3S,8R,9S,10R,13S,14S,17R)-17-乙炔基-13-甲基-2,3,6,7,8,9,10,11,12,13,14,15,16,17-十四氫-1H-環(huán)戊并[A]菲-3,17-二基 二乙酸酯
• 雙醋炔諾醇 標準品
• 雙醋炔諾醇 USP標準品
• 雙醋炔諾醇(CAS號:297-76-7)
• 乙炔二醇二乙酸酯
• 雙醋炔諾醇
• 297-76-7
• 4-ESTREN-17α-ETHYNYL-3β, 17β-DIOL DIACETATE
• (3S,8R,9S,10R,13S,14S,17R)-17-Ethynyl-13-methyl-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,17-diyl diacetate
• ETHYNODIOL DIACETATE /297-76-7
• Ethynodiol diacetate USP/EP/BP
• 19-Norpregn-4-en-20-yne-3,17-diol, diacetate, (3b,17a)-
• acetic acid [(3S,8R,9S,10R,13S,14S,17R)-17-acetyloxy-17-ethynyl-13-methyl-2,3,6,7,8,9,10,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] ester
• Ethynodiol Diacetate (200 mg)
• acetic acid [(3S,8R,9S,10R,13S,14S,17R)-17-acetoxy-17-ethynyl-13-methyl-2,3,6,7,8,9,10,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] ester
• [(3S,8R,9S,10R,13S,14S,17R)-17-acetyloxy-17-ethynyl-13-methyl-2,3,6,7,8,9,10,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] ethanoate
• [(3S,8R,9S,10R,13S,14S,17R)-17-acetyloxy-17-ethynyl-13-methyl-2,3,6,7,8,9,10,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate
• Continuin
• CB-8080
• [(3S,8R,9S,10R,13S,14S,17S)-3-acetyloxy-17-ethynyl-13-methyl-2,3,6,7,8,9,10,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate
• 3β,17β-Diacetoxy-17α-ethynyl-4-estrene
• ETHYLNODIOLACETATE
• 19-Nor-17α-pregn-4-en-20-yne-3β,17-diol diacetate
• etynodiol di(acetate)
• Double vinegar ethynodiol
• Etynodiol acetate
• (3β, 17α)-19-Norpregn-4-en-20-yne-3,17-diol diacetate
• 19-Norpregn-4-en-20-yne-3,17-diol, 3,17-diacetate, (3β,17α)-
• 17a-Ethynyl-4-estren-3b,17-diol diacetate
• 8080 C. B.
• 3-beta,17-beta-Diacetoxy-19-nor-17-alpha-pregn-4-en-20-yne
• 3-beta,17-beta-diacetoxy-17-alpha-ethynyl-4-oestrene
• 3-beta, 17-beta-Diacetoxy-17-alpha-ethynyl-4-oestrene
• 19-Norpregn-4-en-20-yne-3,17-diol, diacetate, (3beta,17alpha)-
• 19-nor-17-alpha-pregn-4-en-20-yne-3-beta,17-diol,diacetate
• 19-Nor-17-alpha-pregn-4-en-20-yne-3-beta,17-diol diacetate
• 19-Nor-17alpha-pregn-4-en-20-yn-3beta,17-diol diacetate
• 17-alpha-ethynylestr-4-ene-3-beta,17-beta-diolacetate
• 4-ESTREN-17-ALPHA-ETHYNYL-3-BETA, 17-BETA-DIOL DIACETATE
• component of Conova
• Cervicundin
• beta-ethynodioldiacetate
• beta-Ethynodiol diacetate
• 8080c.b.