5-氨基酮戊酸芐酯鹽酸鹽
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- CAS號(hào):
- 163271-32-7
- 英文名:
- 5-Aminolevulinic acid benzyl ester hydrochloride
- 英文別名:
- Benzyl-ALA hydrochloride;ALA BENZYL ESTER HYDROCHLORIDE;5-aminolevulinic acid benzyl ester;5-Aminolevulinic acid benzyl ester HCl;Benzyl 5-amino-4-oxopentanoate hydrochloride;AMINOLEVULINIC ACID BENZYL ESTER HYDROCHLORIDE;5-ALA benzyl ester hydrochloride, 10 mM in DMSO;5-AMINOLEVULINIC ACID BENZYL ESTER HYDROCHLORIDE;DELTA-AMINOLEVULINIC ACID BENZYL ESTER HYDROCHLORIDE;5-AMINO-4-OXOPENTANOIC ACID BENZYL ESTER HYDROCHLORIDE
- 中文名:
- 5-氨基酮戊酸芐酯鹽酸鹽
- 中文別名:
- 化合物 T19147;5-氨基酮戊酸芐酯鹽酸鹽;化合物5-ALA BENZYL ESTER HYDROCHLORIDE;化合物5-ALA BENZYL ESTER HYDROCHLORIDE,10 MM DMSO 溶液
- CBNumber:
- CB2259055
- 分子式:
- C12H16ClNO3
- 分子量:
- 257.71
- MOL File:
- 163271-32-7.mol
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5-氨基酮戊酸芐酯鹽酸鹽化學(xué)性質(zhì)
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儲(chǔ)存條件:
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Store at -20°C
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溶解度:
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DMSO: 250 mg/mL (970.08 mM)
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形態(tài):
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Solid
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顏色:
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White to off-white
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5-氨基酮戊酸芐酯鹽酸鹽性質(zhì)、用途與生產(chǎn)工藝
5-ALA benzyl ester hydrochloride (Benzyl-ALA hydrochloride) 是一種用作光檢測(cè)器的原卟啉前體。5-ALA benzyl ester hydrochloride 誘導(dǎo)原卟啉 IX (PPIX) 在結(jié)腸癌細(xì)胞系中的積聚。
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Human Endogenous Metabolite
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5-ALA benzyl ester hydrochloride (Benzyl-ALA hydrochloride) (0.6-0.12 mM; 3 h) induces protoporphyrin IX (PPIX) accumulation in colon carcinoma cell lines SW480.
Reducing the dose of 5-ALA benzyl ester hydrochloride (31 mg/kg; i.v. ; 1 hours) results in a dose-dependent reduction in tumour porphyrin levels.
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Animal Model:
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Female CBA/Gy mouse (CaNT tumour model)
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Dosage:
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31 mg/kg
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Administration:
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i.v. ; 1 hours
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Result:
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Reducing the dose of 5-ALA benzyl ester hydrochloride resulted in a dose-dependent reduction in the concentration of porphyrins accumulating in the CaNT tumour.
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5-氨基酮戊酸芐酯鹽酸鹽
上下游產(chǎn)品信息
上游原料
下游產(chǎn)品
163271-32-7, 5-氨基酮戊酸芐酯鹽酸鹽 相關(guān)搜索:
- Fatty & Aliphatic Acids, Esters, Alcohols & Derivatives
- 抑制劑
- 醫(yī)藥中間體
- 化合物5-ALA BENZYL ESTER HYDROCHLORIDE,10 MM DMSO 溶液
- 化合物5-ALA BENZYL ESTER HYDROCHLORIDE
- 化合物 T19147
- 5-氨基酮戊酸芐酯鹽酸鹽
- 163271-32-7
- 5-ALA benzyl ester hydrochloride, 10 mM in DMSO
- Endogenous Metabolite,accumulation,5 ALA benzyl ester hydrochloride,SW480,photodetection,protoporphyrin,5-ALA benzyl ester,Inhibitor,inhibit,Benzyl-ALA,colon,5ALA benzyl ester hydrochloride,carcinoma
- Pentanoic acid, 5-amino-4-oxo-, phenylmethyl ester, hydrochloride (1:1)
- Benzyl-ALA hydrochloride
- 5-aminolevulinic acid benzyl ester
- Benzyl 5-amino-4-oxopentanoate hydrochloride
- AMINOLEVULINIC ACID BENZYL ESTER HYDROCHLORIDE
- ALA BENZYL ESTER HYDROCHLORIDE
- 5-AMINOLEVULINIC ACID BENZYL ESTER HYDROCHLORIDE
- 5-AMINO-4-OXOPENTANOIC ACID BENZYL ESTER HYDROCHLORIDE
- DELTA-AMINOLEVULINIC ACID BENZYL ESTER HYDROCHLORIDE
- 5-Aminolevulinic acid benzyl ester HCl