L-抗壞血酸-2-單磷酸酯三環(huán)己銨鹽
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- CAS號(hào):
- 23313-12-4
- 英文名:
- L-ASCORBIC ACID 2-MONOPHOSPHATE TRI-CYCLOHEXYLAMMONIUM SALT
- 英文別名:
- Vitamin C phosphate;Ascorbyl-2-phosphate;ascorbate-2-phosphate;Ascorbyl monophosphate;Ascorbyl-2-monophosphate;Ascorbic Acid Impurity 6;2-Phospho-L-ascorbic acid;MIJPAVRNWPDMOR-ZAFYKAAXSA-N;L-Ascorbic acid, 2-(dihydrogen phosphate);LAscorbic acid 2phosphate,L Ascorbic acid 2 phosphate
- 中文名:
- L-抗壞血酸-2-單磷酸酯三環(huán)己銨鹽
- 中文別名:
- 2-磷酸抗壞血酸;抗壞血酸2-磷酸鹽;維生素C磷酸酯35%;化合物 T19390;L-抗壞血酸-2-單磷酸酯三環(huán)己銨鹽;維生素C磷酸酯(L-抗壞血酸-2-磷酸酯)
- CBNumber:
- CB1505885
- 分子式:
- C6H9O9P
- 分子量:
- 256.1
- MOL File:
- 23313-12-4.mol
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L-抗壞血酸-2-單磷酸酯三環(huán)己銨鹽化學(xué)性質(zhì)
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沸點(diǎn):
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682.7±65.0 °C(Predicted)
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密度:
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2.01±0.1 g/cm3(Predicted)
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酸度系數(shù)(pKa):
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1.38±0.10(Predicted)
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形態(tài):
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Solid
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顏色:
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Off-white to light yellow
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L-抗壞血酸-2-單磷酸酯三環(huán)己銨鹽性質(zhì)、用途與生產(chǎn)工藝
L-ascorbic?acid?2-phosphate 是一種長效的維生素 C 衍生物 (vitamin?C?derivative)，可以刺激膠原蛋白的表達(dá)和形成。L-ascorbic?acid?2-phosphate 可以作為培養(yǎng)基補(bǔ)充人脂肪干細(xì)胞 (hASCs) 的成骨分化。L-ascorbic?acid?2-phosphate 增加成骨細(xì)胞分化過程中 hASC 中的堿性磷酸酶 (ALP) 活性和 runx2A 的表達(dá)。
IC50: alkaline phosphatase (ALP); collagen formation; runx2A
L-Ascorbic acid 2-phosphate (0.1-1.5 mM; 2 to 3 weeks with medium exchange every 2 to 3 days) significantly stimulates cell growth, whereas addition of l-Ascorbic acid (Asc)? achieves only weak growth stimulation. A combination of Asc-2P and bFGF significantly increases cell growth, but supplementation with EGF and/or insulin does not have any additional effect?.
L-Ascorbic?acid?2-phosphate (50 μM-250 μM) is needed for the effective osteogenic differentiation of human adipose stem cells (hASCs), and higher concentrations of AsA2-P results in increased runx2 expression and ALP activity. The highest proliferation, ALP activity and runx2 expression is achieved with 150 μM AsA2-P and 10 nM dexamethasone (Dex), and 250 μM AsA2-P and 5 nM Dex.
Cell Proliferation Assay
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Cell Line:
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Human?corneal?endothelial?cells?(HCECs)
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Concentration:
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0.1 mM; 0.3 mM; 1.5 mM
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Incubation Time:
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2 to 3 weeks with medium exchange every 2 to 3 days
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Result:
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Stimulated HCEC cells growth.
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L-抗壞血酸-2-單磷酸酯三環(huán)己銨鹽
上下游產(chǎn)品信息
上游原料
下游產(chǎn)品
L-抗壞血酸-2-單磷酸酯三環(huán)己銨鹽
生產(chǎn)廠家
23313-12-4, L-抗壞血酸-2-單磷酸酯三環(huán)己銨鹽 相關(guān)搜索:
- 抑制劑
- 化學(xué)試劑
- 有機(jī)產(chǎn)品
- 維生素C 系列
- 食品添加劑
- 有機(jī)化工原料
- 中間體
- C24H48N3O9P
- 維生素C磷酸酯35%
- 抗壞血酸2-磷酸鹽
- 2-磷酸抗壞血酸
- 化合物 T19390
- 維生素C磷酸酯(L-抗壞血酸-2-磷酸酯)
- L-抗壞血酸-2-單磷酸酯三環(huán)己銨鹽
- 23313-12-4
- LAscorbic acid 2phosphate,L Ascorbic acid 2 phosphate
- 2-Phospho-L-ascorbic acid
- MIJPAVRNWPDMOR-ZAFYKAAXSA-N
- Ascorbic Acid Impurity 6
- [2-(1,2-dihydroxyethyl)-3-hydroxy-5-oxo-2H-furan-4-yl] dihydrogen phosphate
- L-Ascorbic acid, 2-(dihydrogen phosphate)
- Ascorbyl-2-phosphate
- Ascorbyl-2-monophosphate
- Ascorbyl monophosphate
- ascorbate-2-phosphate
- l-ascorbic acid 2-monophosphate tris-cyclohexylammonium salt
- Vitamin C phosphate