N-(2-(9H-咔唑-1-基)苯基)乙酰胺
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- CAS號(hào):
- 2143475-98-1
- 英文名:
- GeA-69
- 英文別名:
- eA-69;GeA-69;GeA-69 >=98% (HPLC);N-(2-(9H-Carbazol-1-yl)phenyl)acetamide;Acetamide, N-[2-(9H-carbazol-1-yl)phenyl]-;PARP,HeLa,GeA-69,U-2 OS,GeA69,cytotoxicity,DNA damage repair mechanism,intact cell,Inhibitor,cell permeable,GeA 69,inhibit,poly ADP ribose polymerase,HEK293
- 中文名:
- N-(2-(9H-咔唑-1-基)苯基)乙酰胺
- 中文別名:
- GEA-69游離態(tài);化合物GEA-69;N-(2-(9H-咔唑-1-基)苯基)乙酰胺
- CBNumber:
- CB04667935
- 分子式:
- C20H16N2O
- 分子量:
- 300.35
- MOL File:
- 2143475-98-1.mol
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N-(2-(9H-咔唑-1-基)苯基)乙酰胺化學(xué)性質(zhì)
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沸點(diǎn):
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568.3±25.0 °C(Predicted)
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密度:
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1.281±0.06 g/cm3(Predicted)
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儲(chǔ)存條件:
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Keep in dark place,Sealed in dry,Room Temperature
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溶解度:
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DMSO:92.5(Max Conc. mg/mL);307.96(Max Conc. mM)
Ethanol:10.0(Max Conc. mg/mL);33.29(Max Conc. mM)-
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酸度系數(shù)(pKa):
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14.96±0.70(Predicted)
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形態(tài):
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Solid
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顏色:
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White to off-white
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N-(2-(9H-咔唑-1-基)苯基)乙酰胺性質(zhì)、用途與生產(chǎn)工藝
GeA-69 是一種可透過細(xì)胞的選擇性變構(gòu)抑制劑，靶向 macrodomain 2 (MD2) of poly-adenosine-diphosphate-ribose polymerase 14 (PARP14) ，其Kd值為860 nM。
| Target | Value |
PARP14-MD2
(Cell-free assay)
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860 nM(Kd)
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N-(2-(9H-咔唑-1-基)苯基)乙酰胺
上下游產(chǎn)品信息
上游原料
下游產(chǎn)品
| 更新日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS編號(hào) | 包裝 | 價(jià)格 |
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| 2024/11/08 | HY-108708 | N-(2-(9H-咔唑-1-基)苯基)乙酰胺
GeA-69 | 2143475-98-1 | 5mg | 350元 |
| 2024/11/08 | HY-108708 | N-(2-(9H-咔唑-1-基)苯基)乙酰胺
GeA-69 | 2143475-98-1 | 10mM * 1mLin DMSO | 385元 |
N-(2-(9H-咔唑-1-基)苯基)乙酰胺
生產(chǎn)廠家
2143475-98-1, N-(2-(9H-咔唑-1-基)苯基)乙酰胺 相關(guān)搜索:
- 抑制劑
- 藥靶配體
- 化合物GEA-69
- N-(2-(9H-咔唑-1-基)苯基)乙酰胺
- GEA-69游離態(tài)
- 2143475-98-1
- PARP,HeLa,GeA-69,U-2 OS,GeA69,cytotoxicity,DNA damage repair mechanism,intact cell,Inhibitor,cell permeable,GeA 69,inhibit,poly ADP ribose polymerase,HEK293
- N-(2-(9H-Carbazol-1-yl)phenyl)acetamide
- GeA-69 >=98% (HPLC)
- Acetamide, N-[2-(9H-carbazol-1-yl)phenyl]-
- eA-69
- GeA-69