96-88-8
中文名稱
2-甲基-2,6-壬二烯-1-胺
英文名稱
N-(2,6-dimethylphenyl)-1-methylpiperidine-2-carboxamide
CAS
96-88-8
分子式
C15H22N2O
分子量
246.348
MOL 文件
96-88-8.mol
更新日期
2024/06/13 11:53:39
96-88-8 結(jié)構(gòu)式
基本信息
中文別名
美哌卡因6-壬二烯-1-胺
2-甲基-2,6-壬二烯-1-胺
N-(26-二甲基苯基)-1-甲基哌啶-2-甲酰胺
英文別名
C07528Carbocain
Polocaine
Mepicaine
Carbocaine
Scandicain
Scandicaine
DL-Mepivacaine
1-Methyl-2',6'-pipecoloxylidide
Mepivacaine (base and/or unspecified salts)
所屬類別
有機原料：氨基化合物物理化學(xué)性質(zhì)
熔點150-151°
沸點389.35°C (rough estimate)
密度0.9978 (rough estimate)
折射率1.6280 (estimate)
儲存條件-20°C儲存
溶解度DMF: 30 mg/ml; DMSO: 25 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
酸度系數(shù)(pKa)14.85±0.70(Predicted)
形態(tài)結(jié)晶固體
顏色White to off-white
水溶解性2.217g/L(25 ºC)
EPA化學(xué)物質(zhì)信息2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-methyl- (96-88-8)
2-甲基-2,6-壬二烯-1-胺價格(試劑級)
| 報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
| 2024/08/19 | S5392 | 2-甲基-2,6-壬二烯-1-胺 Mepivacaine | 96-88-8 | 25mg | 794.84元 |
常見問題列表
生物活性
Mepivacaine 是一種酰胺型藥劑，可暫時使局部失去知覺。Mepivacaine 與神經(jīng)元細(xì)胞膜上特定的電壓門控鈉離子通道結(jié)合，抑制鈉離子內(nèi)流和膜去極化。體外研究
Mepivacaine binds to specific voltage-gated sodium ion channels in neuronal cell membranes, which inhibits both sodium influx and membrane depolarization. This leads to a blockage of nerve impulse initiation and conduction and results in a reversible loss of sensation. Compared to other local anesthetics, this agent has a more rapid onset and moderate duration of action.
Mepivacaine has a reasonably rapid onset (more rapid than that of procaine) and medium duration of action (shorter than that of procaine).
Mepivacaine displays a preferential use-dependent block of Na(v)1.8, S(-)-bupivacaine displays a preference for TTXs Na(+) channels.