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924641-59-8

中文名稱 [4-[[5-氟-4-[2-甲基-1-(1-甲基乙基)-1H-咪唑-5-基]-2-嘧啶基]氨基]苯基][(3S)-3-(甲氨基)-1-吡咯烷]甲酮
英文名稱 [4-[[5-Fluoro-4-[2-methyl-1-(1-methylethyl)-1H-imidazol-5-yl]-2-pyrimidinyl]amino]phenyl][(3S)-3-(methylamino)-1-pyrrolidinyl]Methanone
CAS 924641-59-8
分子式 C23H28FN7O
分子量 437.51
MOL 文件 924641-59-8.mol
更新日期 2024/07/01 17:51:36
924641-59-8 結(jié)構(gòu)式 924641-59-8 結(jié)構(gòu)式

基本信息

中文別名
化合物AZD-5597
(S)-(4-((5-氟-4-(1-異丙基-2-甲基-1H-咪唑-5-基)嘧啶-2-基)氨基)苯基)(3-(甲基氨基)吡咯烷哌嗪-1-基)甲酮
[4-[[5-氟-4-[2-甲基-1-(1-甲基乙基)-1H-咪唑-5-基]-2-嘧啶基]氨基]苯基][(3S)-3-(甲氨基)-1-吡咯烷]甲酮
[4-[[5-氟-4-[2-甲基-1-(1-甲基乙基)-1H-咪唑-5-基]-2-嘧啶基]氨基]苯基][(3S)-3-(甲基氨基)-1-吡咯烷基]甲酮
英文別名
CS-1058
AZD 5597
pyrimidin-2-yl)
(3-(methylamino)
AZD 5597
AZD5597
-(4-((5-Fluoro-4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)
(S)-(4-((5-Fluoro-4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)pyrimidin-2-yl)amino)phenyl)(3-(met
(S)-(4-((5-Fluoro-4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)pyrimidin-2-yl)amino)phenyl)(3-(methyl
(S)-(4-((5-Fluoro-4-(1-isopropyl-2-Methyl-1H-iMidazol-5-yl)pyriMidin-2-yl)aMino)phenyl)(3-(MethylaMino)pyrrolidin-1-yl)Methanone
4-[[5-Fluoro-4-[2-methyl-1-(1-methylethyl)-1H-imidazol-5-ly]-2-pyrimidinyl]amino]phenyl][(3S)-3-(methylamino)-1-pyrrolidinyl]methanone
所屬類別
生物化工:激動(dòng)劑抑制劑

物理化學(xué)性質(zhì)

沸點(diǎn)679.0±65.0 °C(Predicted)
密度1.32
儲(chǔ)存條件2-8°C(protect from light)
溶解度≥1.82 mg/mL in H2O with ultrasonic; ≥12.7 mg/mL in EtOH; ≥15.65 mg/mL in DMSO
酸度系數(shù)(pKa)9.66±0.20(Predicted)
形態(tài)固體
顏色Off-white to light yellow
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