916888-47-6
916888-47-6 結(jié)構(gòu)式
基本信息
英文別名
Resolvin D35,7,9,13,15,19-Docosahexaenoic acid, 4,11,17-trihydroxy-, (4S,5Z,7E,9E,11R,13Z,15E,17S,19Z)-
物理化學(xué)性質(zhì)
儲(chǔ)存條件-20°C儲(chǔ)存
溶解度DMF: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.4): 0.05 mg/ml
形態(tài)Liquid
顏色Colorless to light yellow
Resolvin D3價(jià)格(試劑級(jí))
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2024/11/08 | HY-136540 | Resolvin D3 Resolvin D3 | 916888-47-6 | 25μg(265.6μM * 250μL in Ethanol) | 8800元 |
常見(jiàn)問(wèn)題列表
生物活性
Resolvin D3 (RvD3) 是二十二碳六烯酸 (DHA) 衍生的介體。Resolvin D3 在關(guān)節(jié)炎中失調(diào)，可減輕關(guān)節(jié)炎癥。體外研究
RvD3 (RvD3; 10 nM) significantly inhibits tumor necrosis factor-α–induced NF-κB activation in A549 epithelial cells.
體內(nèi)研究
Resolvin D3 (RvD3; 100 ng/100 μl; IP; daily for 6 days) alleviates arthritis progression, reduces edema and limits leukocyte numbers in murine K/BxN-serum induced arthritis.
| Animal Model: | Male C57Bl/6 mice (12 weeks old) or ALX/fpr2/3 KO mice |
| Dosage: | 100 ng/100 μl |
| Administration: | IP; daily for 6 days |
| Result: | Alleviated arthritis progression, reduced edema and limited leukocyte numbers in murine K/BxN-serum induced arthritis. |