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877130-28-4

中文名稱 (R)-6-環(huán)戊基-6-[2-(2,6-二乙基吡啶-4-基)乙基]-3-[(5,7-二甲基-[1,2,4]三唑并[1,5-A]嘧啶-2-基)甲基]-4-羥基-5,6-二氫-2H-吡喃-2-酮
英文名稱 (R)-6-Cyclopentyl-6-[2-(2,6-diethylpyridin-4-yl)ethyl]-3-[(5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)methyl]-4-hydroxy-5,6-dihydro-2H-pyran-2-one
CAS 877130-28-4
分子式 C29H37N5O3
分子量 503.64
MOL 文件 877130-28-4.mol
877130-28-4 結(jié)構(gòu)式 877130-28-4 結(jié)構(gòu)式

基本信息

中文別名
化合物 T15282
化合物FILIBUVIR
(R)-6-環(huán)戊基-6-[2-(2,6-二乙基吡啶-4-基)乙基]-3-[(5,7-二甲基-[1,2,4]三唑并[1,5-A]嘧啶-2-基)甲基]-4-羥基-5,6-二氫-2H-吡喃-2-酮
英文別名
Filibuvir
Pf-00868554
Unii-198J479Y2l
Filibuvir >=98% (HPLC)
Filibuvir (PF-00868554
(2R)-2-cyclopentyl-2-[2-(2,6-diethylpyridin-4-yl)ethyl]-5-[(5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)methyl]-4-hydroxy-3H-pyran-6-one
6-cyclopentyl-6-(2-(2,6-diethylpyridin-4-yl)ethyl)-3-((5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)methyl)-4-hydroxy-5,6-dihydro-2H-pyran-2-one
(6R)-6-Cyclopentyl-6-[2-(2,6-diethyl-4-pyridinyl)ethyl]-3-[(5,7-dimethyl[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)methyl]-5,6-dihydro-4-hydroxy-2H-pyran-2-one
(6R)-6-Cyclopentyl-6-(2-(2,6-diethylpyridin-4-yl)ethyl)-3-((5,7-dimethyl(1,2,4)triazolo(1,5-A)pyrimidin-2-yl)methyl)-4-hydroxy-5,6-dihydro-2H-pyran-2-one
(R)-6-Cyclopentyl-6-[2-(2,6-diethylpyridin-4-yl)ethyl]-3-[(5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)methyl]-4-hydroxy-5,6-dihydro-2H-pyran-2-one
所屬類別
醫(yī)藥中間體:乙基吡啶

物理化學(xué)性質(zhì)

密度1.29
儲存條件room temp
溶解度DMSO:可溶10mg/mL,澄清
酸度系數(shù)(pKa)4.50±1.00(Predicted)
形態(tài)粉末
顏色白色至米色

安全數(shù)據(jù)

WGK Germany3
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