794572-10-4
中文名稱
ML-184
英文名稱
ML-184
CAS
794572-10-4
分子式
C25H34N4O3S
分子量
470.63
MOL 文件
794572-10-4.mol
更新日期
2023/03/20 15:41:27
794572-10-4 結構式
基本信息
中文別名
化合物ML-1843-[4-(2,3-二甲基苯基)哌嗪-1-羰基]-N,N-二甲基-4-(吡咯烷-1-基)苯-1-磺酰胺
英文別名
ML-1843-[4-(2,3-dimethylphenyl)piperazine-1-carbonyl]-N,N-dimethyl-4-pyrrolidin-1-ylbenzenesulfonamide
3-[[4-(2,3-Dimethylphenyl)-1-piperazinyl]carbonyl]-N,N-dimethyl-4-(1-pyrrolidinyl)benzenesulfonamide
3-[4-(2,3-dimethylphenyl)piperazine-1-carbonyl]-N,N-dimethyl-4-(pyrrolidin-1-yl)benzene-1-sulfonamide
Benzenesulfonamide, 3-[[4-(2,3-dimethylphenyl)-1-piperazinyl]carbonyl]-N,N-dimethyl-4-(1-pyrrolidinyl)-
所屬類別
有機原料：雜環(huán)化合物物理化學性質
儲存條件-20°C儲存
溶解度DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:4): 0.2 mg/ml; DMSO: 20 mg/ml; Ethanol: 1 mg/ml
形態(tài)結晶固體
顏色White to off-white
應用領域
用途一
CID2440433, also known as ML-184, is a potent synthetic agonist of GPR55 (EC50 = 0.26 μM). GPR55 is a G protein-coupled receptor that is weakly activated by some cannabinoids (CBs) at nM concentrations but displays a 5- to 10-fold greater stimulation in response to 1 μM lysophosphatidylinositol (LPI).