79103-90-5
中文名稱
遠(yuǎn)志皂苷 F
英文名稱
Polygalasaponin XXXI
CAS
79103-90-5
分子式
C75H112O36
分子量
1589.69
MOL 文件
79103-90-5.mol
更新日期
2023/11/22 17:15:50
79103-90-5 結(jié)構(gòu)式
基本信息
中文別名
遠(yuǎn)志皂苷 F瓜子金皂苷XXXI
瓜子金皂苷XXXI標(biāo)準(zhǔn)品
瓜子金皂苷XXXI(對(duì)照品)
遠(yuǎn)志皂苷F瓜子金皂苷XXXI
英文別名
Onjisaponin FPolygalasaponin XXX
Polygalasaponin XXXI
Onjisaponin F Polygalasaponin XXXI
Olean-12-ene-23,28-dioic acid, 3-(β-D-glucopyranosyloxy)-2,27-dihydroxy-, 28-[O-D-apio-β-D-furanosyl-(1→3)-O-[O-α-L-arabinopyranosyl-(1→3)-β-D-xylopyranosyl-(1→4)]-O-6-deoxy-α-L-mannopyranosyl-(1→2)-6-deoxy-4-O-[(2E)-1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propen-1-yl]-β-D-galactopyranosyl] ester, (2β,3β...
所屬類別
生物化工：植物提取物物理化學(xué)性質(zhì)
密度1.53±0.1 g/cm3(Predicted)
儲(chǔ)存條件Inert atmosphere,2-8°C
溶解度Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
酸度系數(shù)(pKa)4.14±0.70(Predicted)
形態(tài)粉末
顏色White to off-white
常見(jiàn)問(wèn)題列表
生物活性
Polygalasaponin XXXI (Onjisaponin F) 是鼻內(nèi)注射流感 HA 疫苗的有效佐劑，可保護(hù)流感病毒感染體外研究
Polygalasaponin XXXI (Onjisaponin F) also enhances anti-HA IgA and IgG Ab titers in the nasal wash, whereas Onjisaponins E and G enhances only anti-HA IgA Ab titer significantly. Polygalasaponin XXXI can induce protective immunity against intranasal infection by influenza virus.
Polygalasaponin XXXI (Onjisaponin F) (1 or 10 μg/mL) also induces ChAT mRNA level in rat basal forebrain cells.
體內(nèi)研究
Intranasal vaccination with Polygalasaponin XXXI (Onjisaponin F) inhibits proliferation of mouse adapted influenza virus A/PR/8/34 in bronchoalveolar lavages of infected mice.