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778274-97-8

中文名稱 NULL
英文名稱 N-(2-hydroxyethyl)-4-(6-(4-(trifluoromethoxy)phenylamino)pyrimidin-4-yl)benzamide
CAS 778274-97-8
分子式 C20H17F3N4O3
分子量 418.37
MOL 文件 778274-97-8.mol
更新日期 2023/02/22 11:54:00
778274-97-8 結構式 778274-97-8 結構式

基本信息

中文別名
化合物MULTI-KINASE INHIBITOR I
英文別名
MDK74978
MDK74978
MDK-74978
Multi-kinase inhibitor 1
Multi-kinase inhibitor I
MDK74978(Multi-kinase inhibitor)
MDK 74978. Multi-kinase inhibitor I
MDK74978
MDK-74978
MDK 74978. MULTI-KINASE INHIBITOR I
N-(2-hydroxyethyl)-4-(6-(4-(trifluoromethoxy)phenylamino)pyrimidin-4-yl)benzamide
Benzamide, N-(2-hydroxyethyl)-4-[6-[[4-(trifluoromethoxy)phenyl]amino]-4-pyrimidinyl]-
所屬類別
生物化工:激動劑抑制劑

物理化學性質

形態(tài)Solid
顏色Off-white to yellow

常見問題列表

生物活性
Multi-kinase inhibitor 1 是一種有效的多激酶 (multi-kinase) 抑制劑。Multi-kinase inhibitor 1 有用于導致與酪氨酸激酶活性異?;蚴Э赜嘘P的疾病或失調的潛力,特別是與 PDGF-R,c-Kit 和 Bcr-abl 活性相關的疾病。
靶點

PDGFR

Bcr-Abl

體外研究

Multi-kinase inhibitor 1 (compound 68) is a potent multi-kinase inhibitor. The protein kinases represent a large family of proteins, which play a central role in the regulation of a wide variety of cellular processes and maintaining control over cellular function. These kinases include receptor tyrosine kinases, such as platelet derived growth factor receptor kinase(PDGF-R), the receptor kinase for stem cell factor, c-Kit, and non-receptor tyrosine kinases, such as the fusion kinase Bcr-abl.

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