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68813-55-8

中文名稱 酚嘧啶 撲蟯靈
英文名稱 OXANTEL PAMOATE
CAS 68813-55-8
分子式 C49H48N4O8
分子量 820.93
MOL 文件 68813-55-8.mol
更新日期 2023/03/20 15:41:17
68813-55-8 結(jié)構(gòu)式 68813-55-8 結(jié)構(gòu)式

基本信息

中文別名
奧克太
酚嘧啶
酚嘧啶 撲蟯靈
含 4,4′-亞甲基雙(3-羥基-2-萘甲酸) 的 1-甲基-2-(3-羥基苯乙烯基)-1,4,5,6-四氫嘧啶化合物
英文別名
OXANTEL PAMOATE
Oxantel Ebonate
Einecs 272-332-6
Octahydronaphthol
Parasite,inhibit,Inhibitor,Oxantel Pamoate,Oxantel
1-METHYL-2-[3-HYDROXYPHENYLETHENYL]-1,4,5,6-TETRAHYDROPYRIMIDINE COMPOUND WITH 4,4'-METHYLENEBIS[3-HYDROXY-2-NAPHTHOIC ACID]
1-methyl-2-(3-hydroxyphenylethenyl)-1,4,5,6-tetrahydropyrimidine compound with 4,4'-methylenebis(3-hydroxy-2-naphthoic acid)
4,4'-Methylenebis[3-hydroxy-2-naphthalenecarboxylic Acid 3-[(1E)-2-(1,4,5,6-Tetrahydro-1-Methyl-2-pyriMidinyl)ethenyl]phenol
(E)-3-[2-(1,4,5,6-Tetrahydro-1-Methyl-2-pyriMidinyl)ethenyl]phenol 4,4'-Methylenebis[3-hydroxy-2-naphthalenecarboxylate] Salt
4,4'-methylenebis[3-hydroxy-2-naphthoic] acid, compound with (E)-3-[2-(1,4,5,6-tetrahydro-1-methylpyrimidin-2-yl)vinyl]phenol (1:1)
所屬類別
分析化學(xué):法醫(yī)和獸醫(yī)標(biāo)準(zhǔn)品

物理化學(xué)性質(zhì)

熔點(diǎn)>224°C (dec.)
儲(chǔ)存條件Amber Vial, Refrigerator, Under inert atmosphere
溶解度可溶于DMSO(略微加熱)、甲醇(略微加熱)
形態(tài)neat
顏色白色至灰白色
InChIKeyWSYDAPQDBDVYIO-QEFJDTIGSA-N

安全數(shù)據(jù)

危險(xiǎn)性符號(hào)(GHS)GHS hazard pictograms
GHS07
警示詞警告
危險(xiǎn)性描述H302-H315-H319-H335
防范說(shuō)明P261-P305+P351+P338
WGK Germany3
酚嘧啶 撲蟯靈價(jià)格(試劑級(jí))
報(bào)價(jià)日期產(chǎn)品編號(hào)產(chǎn)品名稱CAS號(hào)包裝價(jià)格
2024/11/08HY-B1344酚嘧啶 撲蟯靈
Oxantel pamoate
68813-55-8100mg200元
2024/11/08HY-B1344酚嘧啶 撲蟯靈
Oxantel pamoate
68813-55-810mM * 1mLin DMSO220元
2024/11/08S5722酚嘧啶 撲蟯靈
Oxantel Pamoate
68813-55-825mg795.36元

常見(jiàn)問(wèn)題列表

生物活性
Oxantel pamoate 是一種廣泛使用的驅(qū)蟲(chóng)劑,有效針對(duì)Trichuris muris 和鉤蟲(chóng)。
靶點(diǎn)

Antiparasitic

體內(nèi)研究

The activity of the veterinary drug Oxantel pamoate is studied against Trichuris muris , Ancylostoma ceylanicum and Necator americanus . An ED 50 s of 4.7 mg/kg is calculated for Oxantel pamoate against T. muris in mice. Combinations of Oxantel pamoate with pyrantel pamoate behaved antagonistically (combination index (CI)=2.53). Oxantel pamoate combined with Levamisole, Albendazole or Ivermectin using ratios based on their ED 50 s reveals antagonistic effects (CI=1.27, 1.90 and 1.27, respectively). A highly synergistic effect (CI=0.15) is observed when Oxantel pamoate-mebendazole is administered to T. muris -infected mice. Oxantel pamoate (10 mg/kg) lacks activity against Ancylostoma ceylanicum and Necator americanus .

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