63631-36-7
63631-36-7 結(jié)構(gòu)式
基本信息
中文別名
化合物 T10390化合物ASPERPHENAMATE
英文別名
AuranamideASPERPHENAMATE
N-Benzoyl-L-phenylalanine (S)-2-benzoylamino-3-phenylpropyl ester
(2S)-2-(Benzoylamino)-3-phenylpropanoic acid (2S)-2-(benzoylamino)-3-phenylpropyl ester
物理化學(xué)性質(zhì)
儲(chǔ)存條件-20°C儲(chǔ)存
溶解度DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
形態(tài)固體
顏色White to off-white
常見(jiàn)問(wèn)題列表
生物活性
Asperphenamate 是來(lái)自Aspergillus flatiipes 的真菌代謝物，具有抗腫瘤活性，其對(duì) T47D、MDA-MB-231 和 HL-60 細(xì)胞的IC50 值分別為 92.3 μM、96.5 μM 和97.9 μM。體外研究
Asperphenamate can inhibit cancer cell proliferation by fully inducing autophagy. asperphenamate showed inhibition effects against cathepsin L. At the same time, it also displayed weak inhibitory ability against cathepsin S.