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6019-39-2

中文名稱(chēng) OAC2
英文名稱(chēng) 5-benzoylaminoindole
CAS 6019-39-2
分子式 C15H12N2O
分子量 236.27
MOL 文件 6019-39-2.mol
更新日期 2025/03/06 14:56:12
6019-39-2 結(jié)構(gòu)式 6019-39-2 結(jié)構(gòu)式

基本信息

中文別名
N-(1H-吲哚-5-基)苯甲酰胺
N-(1H-吲哚-5-基)苯甲酰胺, >98%
英文別名
OAC2
CS-2128
OAC2?, >98%
OAC-2
OAC 2
5-benzoylaminoindole
N-(1H-Indol-5-yl)benzaMide
Benzamide, N-1H-indol-5-yl-
所屬類(lèi)別
原料藥:抑制劑

物理化學(xué)性質(zhì)

熔點(diǎn)165 - 167°C
沸點(diǎn)364.3±15.0 °C(Predicted)
密度1.307±0.06 g/cm3(Predicted)
儲(chǔ)存條件Sealed in dry,Room Temperature
溶解度可溶于DMSO(少許)、甲醇(少許)
酸度系數(shù)(pKa)13.99±0.43(Predicted)
形態(tài)固體
顏色淡黃色

安全數(shù)據(jù)

危險(xiǎn)性符號(hào)(GHS)GHS hazard pictograms
GHS07
警示詞警告
危險(xiǎn)性描述H302-H317
防范說(shuō)明P280

圖譜信息

OAC2價(jià)格(試劑級(jí))
報(bào)價(jià)日期產(chǎn)品編號(hào)產(chǎn)品名稱(chēng)CAS號(hào)包裝價(jià)格
2025/02/08HY-12884OAC26019-39-25 mg337元
2025/02/08HY-12884OAC2
OAC2
6019-39-210mM * 1mLin DMSO370元
2025/02/08HY-12884OAC2
OAC2
6019-39-210mg559元

常見(jiàn)問(wèn)題列表

生物活性
OAC-2是transcription factor 4 (OCT4)的激活劑,增強(qiáng)iPSC重編程效率。
靶點(diǎn)
TargetValue
OCT4
()
體外研究

Octamer-binding transcription factor 4 (Oct4) is a master regulator of the induction and maintenance of cellular pluripotency, and has crucial roles in early stages of differentiation. It is the only factor that cannot be substituted by other members of the same protein family to induce pluripotency. Oct4 has been shown to be an essential regulator of embryonic stem cell (ESC) pluripotency and key to the reprogramming process. OAC2 is a structural analog of OAC1. OAC2 activates both Oct4 and Nanog reporters to a similar extent as OAC1. OAC1 and its two structural analogs OAC2 and OAC3 enhances reprogramming efficiency fourfold, up to as high as 2.75%, and accelerates the appearance of iPSC colonies 3 to 4 d when used in combination with the four reprogramming factors, Oct4, Sox2, Klf4, and c-Myc.

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