57961-90-7
57961-90-7 結(jié)構(gòu)式
基本信息
中文別名
化合物CENTHAQUINE 英文別名
PMZ-2010Centhaquin
Centhaquine
Centhaquin PMZ-2010
Centhaquin >=98% (HPLC)
Centhaquin (Centhaquine,PMZ-2010)
2-[2-[4-(3-Methylphenyl)-1-piperazinyl]ethyl]quinoline
Quinoline, 2-[2-[4-(3-methylphenyl)-1-piperazinyl]ethyl]-
物理化學(xué)性質(zhì)
儲(chǔ)存條件-20°C儲(chǔ)存
溶解度DMSO: 62.5 mg/mL (188.57 mM)
形態(tài)Solid
顏色Light yellow to yellow
Centhaquine價(jià)格(試劑級(jí))
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2024/11/08 | HY-106690 | Centhaquine Centhaquin | 57961-90-7 | 5mg | 700元 |
| 2024/11/08 | HY-106690 | Centhaquine Centhaquin | 57961-90-7 | 10mM * 1mLin DMSO | 770元 |
| 2024/11/08 | HY-106690 | Centhaquine Centhaquin | 57961-90-7 | 10mg | 1200元 |
常見問(wèn)題列表
生物活性
Centhaquine (Centhaquin) 是一種具有研究出血性休克的潛力的試劑。Centhaquine 在出血模型中可以減少全身血管阻力。體內(nèi)研究
Centhaquine (Centhaquin) (intravenous?injection, 0.01-1.0 mg/kg; intraduodenal administration 1.0-2.5 mg/kg) lowers the blood pressure and reduced the heart rate of anaesthetized and unanaesthetized (decerebrate) cat in a dose-dependent manner. Centhaquine (Centhaquin) (intravertebral arterial injection; 5-10 μg) or by topical application to the exposed ventral surface of medulla or floor of the fourth ventricle causes hypotension and bradycardia as well as reduced the excitability of the vasomotor loci. Centhaquine (Centhaquin;PMZ-2010) (intravenous administration; 0.015mg/kg) can attenuate the deleterious effects of?catecholamines, improving both the macro- and?microcirculation?during CPR.
| Animal Model: | Landrace/Large White piglets |
| Dosage: | 0.015mg/kg |
| Administration: | Intravenous administration; Adrenaline 0.02mg/kg plus Centhaquin 0.015mg/kg |
| Result: | Added to adrenaline improved ROSC rates in a swine model of VF cardiac arrest. |