52906-92-0
52906-92-0 結(jié)構(gòu)式
基本信息
胃動(dòng)素,豬
胃動(dòng)素 (人類,豬)
胃動(dòng)素,豬, ≥97% (HPLC)
MOTILIN, PORCINE
MOTILIN PORCINE ≥97%
FVPIFTYGELQRMQEKERNKGQ
Motilin, porcine, ≥97% (HPLC)
Gastricmotorstimulatorypeptide
Motilin (26-47), human, porcine
GASTRIC MOTOR STIMULATORY PEPTIDE, PORCINE
PHE-VAL-PRO-ILE-PHE-THR-TYR-GLY-GLU-LEU-GLN-ARG-MET-GLN-GLU-LYS-GLU-ARG-ASN-LYS-GLY-GLN
H-PHE-VAL-PRO-ILE-PHE-THR-TYR-GLY-GLU-LEU-GLN-ARG-MET-GLN-GLU-LYS-GLU-ARG-ASN-LYS-GLY-GLN-OH
物理化學(xué)性質(zhì)
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2024/11/08 | HY-P1037 | 胃動(dòng)素 Motilin (26-47), human, porcine | 52906-92-0 | 500μg | 900元 |
| 2024/11/08 | HY-P1037 | 胃動(dòng)素 Motilin (26-47), human, porcine | 52906-92-0 | 1mg | 1500元 |
| 2024/11/08 | HY-P1037 | 胃動(dòng)素 Motilin (26-47), human, porcine | 52906-92-0 | 5mg | 4500元 |
常見問(wèn)題列表
EC50: 0.3 nM (motilin receptor, Chinese hamster ovary cell)
Ki: 2.3 nM (motilin receptor, Chinese hamster ovary cell)
[Bpa 1 ,Ile 13 ]motilin is a full agonist at the motilin receptor that increases intracellular calcium in a concentration-dependent manner (EC 50 = 1.5 ± 0.4 nM). Motilin binds with high affinity (IC 50 0.7± 0.2 nM) to receptors on smooth muscle cells. Motilin selectively activates G(q) and G(13), stimulates G alpha(q)-dependent phosphoinositide (PI) hydrolysis and 1,4,5-trisphosphate (IP(3))-dependent Ca 2+ release, and increases cytosolic free Ca 2+ . Motilin induces a biphasic, concentration-dependent contraction (EC 50 = 1.0 +/- 0.2 nM), consisting of an initial peak followed by a sustained contraction.