519-98-2
519-98-2 結構式
基本信息
咪達唑侖雜質C
4-單甲基氨基安替比林
4-(甲氨基)安替比林
4-(甲基氨基)安替比林
安替比林,4-(甲基氨基)-
METAMIZOLE 雜質C
1,5-二甲基-4-甲基氨基-2-苯基-3-吡唑酮
1,5-二甲基-4-甲基氨基-2-苯基吡唑-3-酮
1,5-二甲基-4-甲基氨基-2-苯基-吡唑-3-酮
Noraminopyrine
noramidopyrine
Methylaminophenazone
Methylaminoantipyrine
Metamizole Impurity C
N-Methylaminophenazone
4-Methylaminophenazone
Monomethylaminoantipyrine
4-(Methylamino)-antipyrine
物理化學性質
| 報價日期 | 產品編號 | 產品名稱 | CAS號 | 包裝 | 價格 |
| 2025/02/08 | HY-135731 | 4-(甲氨基)安替比林 4-Methylamino antipyrine | 519-98-2 | 5 mg | 350元 |
| 2025/02/08 | HY-135731 | 4-(甲氨基)安替比林 4-Methylamino antipyrine | 519-98-2 | 10 mM * 1 mLin DMSO | 385元 |
| 2025/02/08 | HY-135731 | 4-(甲氨基)安替比林 4-Methylamino antipyrine | 519-98-2 | 10 mg | 500元 |
常見問題列表
COX
Metamizole is a prodrug which, at room temperature and in an atmosphere with oxygen, is spontaneously, nonenzymatically converted to 4-Methylamino antipyrine. Subsequently, the N-methyl side chain of 4-Methylamino antipyrine is oxidized to yield 4-formylaminoantipyrine, which is further converted to 4-aminoantipyrine. Metamizole in aqueous solution and in the presence of oxygen consists of a group of several pyrazolone derivatives of which 4-Methylamino antipyrine is pharmacologically the most important.
The aim of this study is to assess the pharmacokinetics of its active metabolites 4-Methylamino antipyrine in male piglets after a single intramuscular injection of Metamizole. Eight healthy male piglets are administered Metamizole (100 mg/kg) intramuscularly. 4-Methylamino antipyrine plasma concentrations are quantitatively detectable from 0.25 to 48 h. The average maximum concentrations of 4-Methylamino antipyrine is of 47.59 mg/mL. The average half-lives is 8.57 h for 4-Methylamino antipyrine.