469-21-6
中文名稱
多西拉敏
英文名稱
DOXYLAMINE
CAS
469-21-6
分子式
C17H22N2O
分子量
270.37
MOL 文件
469-21-6.mol
更新日期
2024/08/07 14:10:10
469-21-6 結(jié)構(gòu)式
基本信息
中文別名
多西拉敏多沙胺雜質(zhì)
英文別名
oxylamineDOXYLAMINE
NCI C60684
DOXYLAMINE USP/EP/BP
Doxylamine Hydrogen inate
2-dimethylaminoethoxyphenylmethyl-2-picoline
alpha-Dimethylaminoethoxyphenylmethyl-2-picoline
2-[a-(2-dimethylaminoethoxy)-a-methylbenzyl]pyridine
dimethyl(2-(1-phenyl-1-(2-pyridyl)ethoxy)ethyl)amine
phenyl-2-pyridylmethyl-b-N,N-dimethylaminoethyl ether
所屬類別
原料藥：抗組胺藥物理化學(xué)性質(zhì)
熔點(diǎn)25°C
沸點(diǎn)bp0.5 137-141°
密度1.0023 (rough estimate)
折射率1.5486 (estimate)
儲(chǔ)存條件-20°C Freezer, Under inert atmosphere
溶解度乙腈（微溶）、氯仿（微溶）、甲醇（微溶）
酸度系數(shù)(pKa)pKa 9.20(H2O
t = 25
c = 0.002–0.01) (Uncertain);4.4 (Uncertain);9.2 (Uncertain)
形態(tài)Oil
顏色無(wú)色
穩(wěn)定性對(duì)溫度敏感
EPA化學(xué)物質(zhì)信息Doxylamine (469-21-6)
安全數(shù)據(jù)
警示詞警告
危險(xiǎn)性描述H302-H315-H319-H335
毒害物質(zhì)數(shù)據(jù)469-21-6(Hazardous Substances Data)
毒性An antihistamine
that formerly was used in pregnant women for antihistaminic
and sedative properties. Although it has excellent
sedative properties, it has been implicated in teratogenesis and
in causing neurobehavioral toxicity and is therefore no longer
used