39967-60-7
39967-60-7 結(jié)構(gòu)式
基本信息
中文別名
脫氧假尿苷2'-脫氧假尿苷
英文別名
Deoxypseudouridine2'-DEOXYPSEUDOURIDINE
2'-Deoxypseudo-D-uridine
2,4(1H,3H)-Pyrimidinedione, 5-(2-deoxy-β-D-erythro-pentofuranosyl)-
5-(2-Deoxy-beta-D-erythro-pentofuranosyl)-2,4(1H,3H)-pyrimidinedione
物理化學(xué)性質(zhì)
熔點(diǎn)220-222 °C(Solv: ethanol (64-17-5); methanol (67-56-1))
密度1.503±0.06 g/cm3(Predicted)
儲(chǔ)存條件-20°C儲(chǔ)存
溶解度DMSO : ≥ 37 mg/mL (162.14 mM)
酸度系數(shù)(pKa)8.52±0.10(Predicted)
形態(tài)Solid
顏色White to off-white
常見問題列表
用途
脫氧假尿苷是一種有用的研究化合物。
生物活性
Deoxypseudouridine 是一種核苷酸類似物。體外研究
Deoxypseudouridine is a nucleotide analog. Ethidium bromide staining of the gel demonstrates that the digestion of carrier DNA in both control and analog DNA samples (including Deoxypseudouridine) occur to the same extent; this indicates that the restriction enzyme is as active in the presence of the modified DNA substrate (including Deoxypseudouridine) as it is in the presence of unmodified (control) DNA. Enzymes that do not contain an AT base pair in their recognition sequence, restrict DNAs substituted with either deoxypseudouridine or deoxytubercidin as efficiently as control.