35927-38-9
中文名稱
維采寧-1
英文名稱
Vicenin -1
CAS
35927-38-9
分子式
C26H28O14
分子量
564.5
MOL 文件
35927-38-9.mol
更新日期
2024/11/05 14:04:20
35927-38-9 結(jié)構(gòu)式
基本信息
中文別名
維采寧-I維采寧-1
葫蘆巴苷 1
英文別名
Vicenin -16-C-Xylosyl-8-C-glucosylapigenin
4',5,7-Trihydroxy-6-xylosyl-8-glucosylflavone
6-C-beta-D-Xylopyranosyl-8-C-beta-D-glucopyranosylapigenin
4H-1-Benzopyran-4-one, 8-β-D-glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl)-6-β-D-xylopyranosyl-
8-beta-D-Glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl)-6-beta-D-xylopyranosyl-4H-1-benzopyran-4-one
物理化學(xué)性質(zhì)
熔點(diǎn)230 °C (decomp)
沸點(diǎn)935.0±65.0 °C(Predicted)
密度1.766±0.06 g/cm3(Predicted)
儲(chǔ)存條件-20°C儲(chǔ)存
溶解度Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
酸度系數(shù)(pKa)5.70±0.40(Predicted)
形態(tài)粉末
顏色粘黃色
常見問題列表
生物活性
Vicenin 1 是從廣金錢草的地上部分分離得到的一種糖基黃酮，對血管緊張素轉(zhuǎn)換酶 (ACE) 有抑制作用，(IC50=52.50 μM)。靶點(diǎn)
IC50: 52.50 μM (ACE)
體外研究
The target-isolated C-glycosylflavone (Vicenin 1) is evaluated for inhibitory activities. Vicenin 1 embodies effective ACE inhibitory activities with an IC 50 value of 52.50 μM. The tested compound 3 (Vicenin 1) shows activity via the generation of chelate complexes within the active center of ACE.