28656-91-9
28656-91-9 結(jié)構式
基本信息
AEROPLYSININ
aeroplysinini
(+)-aeroplysinini
(+)-AEROPLYSININ-1
(+)shy-Aeroplysinin-1
Aeroplysinin (Aeroplysinin-1)
AEROPLYSININ, APLYSINA AEROPHOBA
(+)-AEROPLYSININ-1, APLYSINA AEROPHOBA
4-cyclohexadiene-1-acetonitrile,3,5-dibromo-1,6-dihydroxy-4-methoxy-(1s-tr
物理化學性質(zhì)
| 報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
| 2024/08/19 | HY-19827 | (+)-AEROPLYSININ-1 Aeroplysinin 1 | 28656-91-9 | 100 μg | 5800元 |
常見問題列表
|
Bacterial
|
HIV-1 14.6 μM (IC 50 ) |
Apoptosis
|
Aeroplysinin 1 shows anti-proliferative effect against tumor cells (HT-1080, HTC-116, HeLa, THP-1, NOMO-1 and HL-60 cells), with IC
50
s ranging from 2.3 to 17 μM.
Aeroplysinin-1 also exhibits an antiviral activity toward HIV-1 caused by inhibition of its reverse transcriptase activity.
Aeroplysinin 1 inhibits
P. phosphoreum
,
C. wailesii
,
P. minimum
and HIV with IC
50
s of 3.5, 5.6, 7.0 and 14.6 μM.
Aeroplysinin 1 inhibits human endothelial cells (EVLC-2, HMEC, RF-24, and HUVEC cells), with IC
50
s ranging from 2.6 to 4.7 μM.
(+)-Aeroplysinin-1 (0.25-0.5 μM) blocks the EGF-dependent proliferation of both MCF-7 and ZR-75-1 human breast cancer cells and inhibits the ligand-induced endocytosis of the EGF receptor in vitro.