260980-89-0
中文名稱
260980-89-0
英文名稱
PropanaMide,2-hydroxy-2-Methyl-N-[4-nitro-3-(trifluoroMethyl)phenyl]-3-[(2,2,2-trifluoroacetyl)aMino
CAS
260980-89-0
分子式
C13H11F6N3O5
分子量
403.23
MOL 文件
260980-89-0.mol
更新日期
2024/12/25 09:05:22
260980-89-0 結(jié)構(gòu)式
基本信息
中文別名
化合物TOPILUTAMIDE 英文別名
BP766Fluridil
Topilutamide
Fluridil (Topilutamide)
2-hydroxy-2-methyl-N-(4-nitro-3-(trifluoromethyl)phenyl)-3-(2,2,2-trifluoroacetamido)propanamide
PropanaMide,2-hydroxy-2-Methyl-N-[4-nitro-3-(trifluoroMethyl)phenyl]-3-[(2,2,2-trifluoroacetyl)aMino
(2R)-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-3-[(2,2,2-trifluoroacetyl)amino]propanamide
物理化學(xué)性質(zhì)
熔點(diǎn)144-145 °C
沸點(diǎn)284-289 °C
密度1.588±0.06 g/cm3(Predicted)
儲(chǔ)存條件-20°C儲(chǔ)存
溶解度DMSO : 150 mg/mL (372.00 mM)
酸度系數(shù)(pKa)10.66±0.46(Predicted)
形態(tài)Solid
顏色White to off-white
260980-89-0價(jià)格(試劑級(jí))
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2024/11/08 | HY-19470 | 260980-89-0 Topilutamide | 260980-89-0 | 5mg | 1200元 |
| 2024/11/08 | HY-19470 | 260980-89-0 Topilutamide | 260980-89-0 | 10mM * 1mLin DMSO | 1320元 |
| 2024/11/08 | HY-19470 | 260980-89-0 Topilutamide | 260980-89-0 | 10mg | 1920元 |
常見問題列表
生物活性
Topilutamide 是一種局部非甾體類抗雄激素 (NSAA)。體內(nèi)研究
Prostate cancer is the most common cancer and one of the leading causes of cancer deaths in men. One of the commonly used approaches to treat metastatic prostate cancer is via first-generation nonsteroidal anti-androgens (NSAAs), namely Flutamide, Nilutamide, Bicalutamide and Topilutamide.