2415263-05-5
中文名稱
TP-238 (hydrochloride)
英文名稱
TP-238 (hydrochloride)
CAS
2415263-05-5
分子式
C22H31ClN6O3S
分子量
495.04
MOL 文件
2415263-05-5.mol
2415263-05-5 結(jié)構(gòu)式
應(yīng)用領(lǐng)域
用途一
TP-238 HCl is a chemical probe for the bromodomains of cat eye syndrome chromosome region, candidate 2 (CECR2) and bromodomain PHD finger transcription factor (BPTF). TP-238 binds to CECR2 and BPTF with KD values of 10 and 120 nM, respectively, in an isothermal titration calorimetry (ITC) assay and IC50 values of 30 and 350 nM, respectively, in an AlphaScreen? assay.