2089226-94-6
中文名稱(chēng)
化合物 T16931
英文名稱(chēng)
SRPKIN-1
CAS
2089226-94-6
分子式
C27H21FN2O3S
分子量
472.53
MOL 文件
2089226-94-6.mol
2089226-94-6 結(jié)構(gòu)式
物理化學(xué)性質(zhì)
沸點(diǎn)719.0±60.0 °C(Predicted)
密度1.43±0.1 g/cm3(Predicted)
儲(chǔ)存條件-20°C儲(chǔ)存
溶解度DMSO: ≥ 110 mg/mL (232.79 mM); Water: < 0.1 mg/mL (insoluble)
酸度系數(shù)(pKa)11.52±0.40(Predicted)
形態(tài)Solid
顏色White to off-white
應(yīng)用領(lǐng)域
用途一
JH-XI-05-01 blocks phosphorylation of SR proteins. JX-XI-05-01 is a covalent SRPK1/2 inhibitor that potently converts VEGF from pro-angiogenic to anti-angiogenic isoform.