2055024-41-2
中文名稱
Propargyl-PEG4-Sulfone-PEG4-acid
英文名稱
Propargyl-PEG4-Sulfone-PEG4-acid
CAS
2055024-41-2
分子式
C22H40O12S
分子量
528.61
MOL 文件
2055024-41-2.mol
2055024-41-2 結構式
基本信息
中文別名
炔基-四聚乙二醇-砜-四聚乙二醇-羧酸炔基-四聚乙二醇-SULFONE-四聚乙二醇-羧酸
英文別名
Propargyl-PEG4-Sulfone-PEG4-acid4,7,10,13,19,22,25,28-Octaoxa-16-thiahentriacont-30-ynoic acid, 16,16-dioxide
應用領域
用途一
Propargyl-PEG4-Sulfone-PEG4-acid is a PEG linker containing a propargyl group with a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) forming a stable amide bond. The propargyl groups can react with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield stable triazole linkages. The hydrophilic PEG spacer increases solubility in aqueous media.