2055024-37-6
中文名稱
Acid-PEG4-Sulfone-PEG4-Acid
英文名稱
Acid-PEG4-Sulfone-PEG4-Acid
CAS
2055024-37-6
分子式
C22H42O14S
分子量
562.63
MOL 文件
2055024-37-6.mol
2055024-37-6 結(jié)構(gòu)式
基本信息
中文別名
羧酸-四聚乙二醇-砜-四聚乙二醇-羧酸羧酸-四聚乙二醇-SULFONE-四聚乙二醇-羧酸
英文別名
Sulfone-Bis-PEG4-acidAcid-PEG4-Sulfone-PEG4-Acid
4,7,10,13,19,22,25,28-Octaoxa-16-thiahentriacontanedioic acid, 16,16-dioxide
應(yīng)用領(lǐng)域
用途一
Acid-PEG4-Sulfone-PEG4-acid contains two PEG-acid chains connected by a sulfone group. The sulfone group can be conjugated with thiol groups of proteins. The terminal carboxylic acid can react with primary amines in the presence of activators such as EDC and HATU to form stable amide bonds. The hydrophilic PEG spacer increases the water solubility of the compound in aqueous media.