1801433-90-8
1801433-90-8 結(jié)構(gòu)式
基本信息
2-Propen-1-one, 1-(4,6-dimethoxy-1,3-benzodioxol-5-yl)-2-(2-hydroxyphenyl)-
物理化學(xué)性質(zhì)
| 報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
| 2025/02/05 | HY-119412 | Biliatresone | 1801433-90-8 | 1 mg | 1727元 |
| 2025/02/05 | HY-119412 | 2-Propen-1-one, 1-(4,6-dimethoxy-1,3-benzodioxol-5-yl)-2-(2-hydroxyphenyl)- Biliatresone | 1801433-90-8 | 5mg | 3800元 |
| 2025/02/05 | HY-119412 | 2-Propen-1-one, 1-(4,6-dimethoxy-1,3-benzodioxol-5-yl)-2-(2-hydroxyphenyl)- Biliatresone | 1801433-90-8 | 10mg | 6000元 |
常見問題列表
Biliatresone has a reduction in primary cilia and a dose-dependent decrease in visible microtubules, suggesting that Biliatresone decreases microtubule stability in primary neonatal mouse extrahepatic cholangiocytes.
Biliatresone (2 μg/ml; for 24 hours) shows disruption of the spheroid lumen and abnormal cholangiocyte polarity in mouse cholangiocyte.
Biliatresone exhibits toxicity at doses of 0.065-1.0 μg/mL with a marked reduction and the lethal dose of Biliatresone in a zebrafish assay is 1 μg/mL.
Larvae treated at 5 dpf with low doses of biliatresone [0.0625 μg/ml (0.2 μM) and 0.125 μg/ml (0.4 μM)] shows only subtle gallbladder defects, whereas larvae treated with higher doses has pronounced morphological defects of the gallbladder and extrahepatic ducts.