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178383-76-1

中文名稱 4-羥基奈必洛爾
英文名稱 4-Hydroxy Nebivolol, Hydrochloride Hydrate (Mixture of Diastereomers)
CAS 178383-76-1
分子式 C22H25F2NO5
分子量 421.43
MOL 文件 178383-76-1.mol
178383-76-1 結(jié)構(gòu)式 178383-76-1 結(jié)構(gòu)式

基本信息

中文別名
4-羥基奈必洛爾
奈必洛爾雜質(zhì)12
4-羥基奈比洛爾(非對(duì)映體的混合物)
4-HYDROXY NEBIVOLOL鹽酸鹽 HYDRATE
英文別名
4-Hydroxy Nebivolol
Nebivolol 4-Hydroxy Impurity
4-Hydroxy nebivolol hydrochloride
4-Hydroxy Nebivolol, Hydrochloride Hydrate
4-Hydroxynebivolol (Mixture of diastereoisomers)
4-Hydroxy Nebivolol HCl (Mixture of Diastereomers)
4-Hydroxy Nebivolol, Hydrochloride Hydrate (Mixture of Diastereomers)
4-Hydroxy Nebivolol, Hydrochloride Hydrate_x000b_(Mixture of Diastereomers)
4-Hydroxy Nebivolol, Hydrochloride Hydrate_x005f_x000b_(Mixture of Diastereomers)
2H-1-Benzopyran-2-methanol, 6-fluoro-α-[[[2-(6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl)-2-hydroxyethyl]amino]methyl]-3,4-dihydro-4-hydroxy-

物理化學(xué)性質(zhì)

熔點(diǎn)75-85°C
沸點(diǎn)640.8±55.0 °C(Predicted)
密度1.374±0.06 g/cm3(Predicted)
儲(chǔ)存條件-20°C Freezer, Under Inert Atmosphere
溶解度少許溶于甲醇
酸度系數(shù)(pKa)13.98±0.40(Predicted)
形態(tài)固體
顏色淺棕色至棕色
穩(wěn)定性吸濕性
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