1620278-72-9
中文名稱
TLR7/8激動劑1二鹽酸鹽
英文名稱
1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride
CAS
1620278-72-9
分子式
C22H26ClN5
分子量
395.94
MOL 文件
1620278-72-9.mol
更新日期
2024/11/08 11:28:06
1620278-72-9 結(jié)構(gòu)式
基本信息
中文別名
二鹽酸TLR7/8 AGONIST 11-(4-(氨基甲基)芐基)-2-丁基-1H-咪唑并[4,5-C]喹啉-4-胺二鹽酸鹽
英文別名
TLR7/8 agonist-5d8 agonist 1 dihydrochloride
TLR7/8 Agonist 1 (hydrochloride)
TLR7/8 agonist 1 (dihydrochloride)
1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride
所屬類別
生物化工：生化試劑物理化學性質(zhì)
儲存條件-20°C儲存
溶解度DMSO:83.33(Max Conc. mg/mL);192.72(Max Conc. mM)
形態(tài)固體
顏色Off-white to light yellow
常見問題列表
生物活性
TLR7/8 agonist 1 dihydrochloride 是一種 toll 樣受體 TLR7/TLR8 的雙重激動劑。靶點
TLR7/TLR8
體外研究
TLR7/8 agonist 1 (Compound 5d) shows prominent immunostimulatory activities. TLR7/8 agonist 1 serves as a convenient precursor for the covalent attachment of fluorophores without significant loss of activity. TLR7/8 agonist 1 retains TLR7-agonistic activity with an EC 50 of 20 nM. TLR7/8 agonist 1 (Compound 1) shows substantially different agonistic potencies in human TLR7 (50 nM) and TLR8 (55 nM) primary screens.