1508-76-5
中文名稱
丙環(huán)定鹽酸鹽
英文名稱
PROCYCLIDINE HYDROCHLORIDE
CAS
1508-76-5
分子式
C19H30ClNO
分子量
323.9
MOL 文件
1508-76-5.mol
更新日期
2023/09/08 15:48:11
1508-76-5 結構式
基本信息
中文別名
開馬君卡馬特靈
丙環(huán)定鹽酸鹽
鹽酸丙環(huán)定 USP標準品
1-苯基-1-環(huán)己基-3-吡咯烷丙醇鹽酸鹽
英文別名
D00782kemadrin
Osnervan
Arpicolin
Kemadrin (tn)
PROCYCLIDINE HCL
kemadrinhydrochloride
PROCYCLIDINE HYDROCHLORIDE
(±)-Procyclidine hydrochlorid
Procyclidine hydrochloride (usp)
所屬類別
分析化學：藥典標準品和雜質標準品安全數(shù)據(jù)
警示詞警告
危險性描述H315-H319
危險品標志Xn
危險類別碼20/21/22
安全說明36
WGK Germany3
RTECS號UY1926000
海關編碼2933997500
毒性mouse,LD50,intravenous,14mg/kg (14mg/kg),BEHAVIORAL: TREMORLUNGS, THORAX, OR RESPIRATION: DYSPNEABEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD,British Journal of Pharmacology and Chemotherapy. Vol. 10, Pg. 383, 1955.
應用領域
用途1
An anticholinergic drug used in the treatment parkinson鈥檚 disease. It is also used to treat patients suffering from drug-induced parkinsonism, akathisia and acute dystonia.丙環(huán)定鹽酸鹽價格(試劑級)
| 報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
| 2024/11/08 | HY-B1487 | 丙環(huán)定鹽酸鹽 Procyclidine hydrochloride | 1508-76-5 | 100mg | 600元 |
| 2024/11/08 | HY-B1487 | 丙環(huán)定鹽酸鹽 Procyclidine hydrochloride | 1508-76-5 | 10mM * 1mLin DMSO | 660元 |
常見問題列表
生物活性
Procyclidine hydrochloride 是一種有效的抗膽堿能試劑，也具有NMDA拮抗劑的特性。靶點
NMDA Receptor
體內(nèi)研究
Procyclidine widely used as anti-parkinsonian agents because of their anti-cholinergic action, is also known to have NMDA antagonist properties. Unlike other NMDA antagonists, these agents-because of their anti-cholinergic action-are devoid of neurotoxic side effects. Procyclidine alleviates thermal hyperalgesia in a dose dependent manner; when a marginally effective dose of the agent is combined with an ineffective dose of an alpha(2) adrenergic agonist (Clonidine or Guanabenz), the combination therapy provides effective and long-lasting relief from neuropathic pain.